281d

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[[Image:281d.gif|left|200px]]
[[Image:281d.gif|left|200px]]
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{{Structure
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|PDB= 281d |SIZE=350|CAPTION= <scene name='initialview01'>281d</scene>, resolution 2.380&Aring;
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The line below this paragraph, containing "STRUCTURE_281d", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
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|DOMAIN=
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{{STRUCTURE_281d| PDB=281d | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=281d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=281d OCA], [http://www.ebi.ac.uk/pdbsum/281d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=281d RCSB]</span>
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'''CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC)'''
'''CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC)'''
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==About this Structure==
==About this Structure==
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281D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=281D OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=281D OCA].
==Reference==
==Reference==
Structure of the A-DNA octamer d(GGCATGCC)., Nunn CM, Neidle S, Acta Crystallogr D Biol Crystallogr. 1997 May 1;53(Pt 3):269-73. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15299929 15299929]
Structure of the A-DNA octamer d(GGCATGCC)., Nunn CM, Neidle S, Acta Crystallogr D Biol Crystallogr. 1997 May 1;53(Pt 3):269-73. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/15299929 15299929]
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[[Category: Protein complex]]
 
[[Category: Neidle, S.]]
[[Category: Neidle, S.]]
[[Category: Nunn, C M.]]
[[Category: Nunn, C M.]]
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[[Category: a-dna]]
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[[Category: A-dna]]
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[[Category: double helix]]
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[[Category: Double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:25:15 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:45:52 2008''
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Revision as of 15:25, 3 May 2008

Image:281d.gif

Template:STRUCTURE 281d

CRYSTAL STRUCTURE OF THE A-DNA OCTAMER D(GGCATGCC)


Overview

The crystal structure of the self-complementary DNA octamer d(GGCATGCC) has been determined to a resolution of 2.38 A and R factor of 17.1%. The structure is an A-DNA octamer duplex with Watson-Crick base pairing along its length. This sequence extends the investigation of octamer duplexes of the type d(GGX(4)CC) which assume P6(1) packing within the crystallographic unit cell. The A-DNA duplex is non-linear with a helix axis curvature of 7 degrees and bending towards the DNA minor groove. In view of the biological importance of protein recognition of some A-DNA sequences the minor-groove geometry and helix-axis curvature for this structure is compared with all others of the type d(GGXATXCC).

About this Structure

Full crystallographic information is available from OCA.

Reference

Structure of the A-DNA octamer d(GGCATGCC)., Nunn CM, Neidle S, Acta Crystallogr D Biol Crystallogr. 1997 May 1;53(Pt 3):269-73. PMID:15299929 Page seeded by OCA on Sat May 3 18:25:15 2008

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