292d

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[[Image:292d.gif|left|200px]]
[[Image:292d.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 292d |SIZE=350|CAPTION= <scene name='initialview01'>292d</scene>, resolution 1.000&Aring;
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The line below this paragraph, containing "STRUCTURE_292d", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=MG:MAGNESIUM+ION'>MG</scene>, <scene name='pdbligand=NA:SODIUM+ION'>NA</scene>, <scene name='pdbligand=P24:1-(AMINOETHYL)AMINO-4-AMINOBUTANE'>P24</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE=
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|DOMAIN=
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{{STRUCTURE_292d| PDB=292d | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=292d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=292d OCA], [http://www.ebi.ac.uk/pdbsum/292d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=292d RCSB]</span>
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}}
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'''INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE:THE CRYSTAL STRUCTURE OF THE D(CG)3 AND N-(2-AMINOETHYL)-1,4-DIAMINOBUTANE COMPLEX'''
'''INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE:THE CRYSTAL STRUCTURE OF THE D(CG)3 AND N-(2-AMINOETHYL)-1,4-DIAMINOBUTANE COMPLEX'''
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==About this Structure==
==About this Structure==
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292D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=292D OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=292D OCA].
==Reference==
==Reference==
Interaction between the left-handed Z-DNA and polyamine. The crystal structure of the d(CG)3 and N-(2-aminoethyl)-1,4-diamino-butane complex., Ohishi H, Kunisawa S, van der Marel G, van Boom JH, Rich A, Wang AH, Tomita K, Hakoshima T, FEBS Lett. 1991 Jun 24;284(2):238-44. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2060642 2060642]
Interaction between the left-handed Z-DNA and polyamine. The crystal structure of the d(CG)3 and N-(2-aminoethyl)-1,4-diamino-butane complex., Ohishi H, Kunisawa S, van der Marel G, van Boom JH, Rich A, Wang AH, Tomita K, Hakoshima T, FEBS Lett. 1991 Jun 24;284(2):238-44. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2060642 2060642]
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[[Category: Protein complex]]
 
[[Category: Boom, J H.Van.]]
[[Category: Boom, J H.Van.]]
[[Category: Hakoshima, T.]]
[[Category: Hakoshima, T.]]
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[[Category: Tomita, K.]]
[[Category: Tomita, K.]]
[[Category: Wang, A H.J.]]
[[Category: Wang, A H.J.]]
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[[Category: complexed with n-(2-aminoethyl)-1,4-diaminobutane]]
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[[Category: Double helix]]
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[[Category: double helix]]
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[[Category: Z-dna]]
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[[Category: z-dna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:25:59 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:46:00 2008''
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Revision as of 15:26, 3 May 2008

Image:292d.gif

Template:STRUCTURE 292d

INTERACTION BETWEEN THE LEFT-HANDED Z-DNA AND POLYAMINE:THE CRYSTAL STRUCTURE OF THE D(CG)3 AND N-(2-AMINOETHYL)-1,4-DIAMINOBUTANE COMPLEX


Overview

The DNA fragment d(CG)3 was co-crystallized with N-(2-aminoethyl)-1,4-diaminobutane (PA(24], a chemically synthesized polyamine. The complex crystal contained one polyamine, 3 magnesium cations and one sodium cation per duplex of d(CG)3, and well diffracted the X-ray intensities up to 1.0 A resolution. The d(CG)3 took a left-handed Z-DNA conformation, and the PA(24) molecule electrostatically interacted with the phosphate groups of the d(CG)3 duplex.

About this Structure

Full crystallographic information is available from OCA.

Reference

Interaction between the left-handed Z-DNA and polyamine. The crystal structure of the d(CG)3 and N-(2-aminoethyl)-1,4-diamino-butane complex., Ohishi H, Kunisawa S, van der Marel G, van Boom JH, Rich A, Wang AH, Tomita K, Hakoshima T, FEBS Lett. 1991 Jun 24;284(2):238-44. PMID:2060642 Page seeded by OCA on Sat May 3 18:25:59 2008

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