295d

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[[Image:295d.jpg|left|200px]]
[[Image:295d.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 295d |SIZE=350|CAPTION= <scene name='initialview01'>295d</scene>, resolution 1.500&Aring;
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The line below this paragraph, containing "STRUCTURE_295d", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=DA:2&#39;-DEOXYADENOSINE-5&#39;-MONOPHOSPHATE'>DA</scene>, <scene name='pdbligand=DC:2&#39;-DEOXYCYTIDINE-5&#39;-MONOPHOSPHATE'>DC</scene>, <scene name='pdbligand=DG:2&#39;-DEOXYGUANOSINE-5&#39;-MONOPHOSPHATE'>DG</scene>, <scene name='pdbligand=DT:THYMIDINE-5&#39;-MONOPHOSPHATE'>DT</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE=
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|DOMAIN=
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{{STRUCTURE_295d| PDB=295d | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=295d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=295d OCA], [http://www.ebi.ac.uk/pdbsum/295d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=295d RCSB]</span>
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}}
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'''CRYSTAL AND SOLUTION STRUCTURES OF THE OLIGONUCLEOTIDE D(ATGCGCAT)2: A COMBINED X-RAY AND NMR STUDY'''
'''CRYSTAL AND SOLUTION STRUCTURES OF THE OLIGONUCLEOTIDE D(ATGCGCAT)2: A COMBINED X-RAY AND NMR STUDY'''
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==About this Structure==
==About this Structure==
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295D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=295D OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=295D OCA].
==Reference==
==Reference==
Crystal and solution structures of the oligonucleotide d(ATGCGCAT)2: a combined X-ray and NMR study., Clark GR, Brown DG, Sanderson MR, Chwalinski T, Neidle S, Veal JM, Jones RL, Wilson WD, Zon G, Garman E, et al., Nucleic Acids Res. 1990 Sep 25;18(18):5521-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2216724 2216724]
Crystal and solution structures of the oligonucleotide d(ATGCGCAT)2: a combined X-ray and NMR study., Clark GR, Brown DG, Sanderson MR, Chwalinski T, Neidle S, Veal JM, Jones RL, Wilson WD, Zon G, Garman E, et al., Nucleic Acids Res. 1990 Sep 25;18(18):5521-8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/2216724 2216724]
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[[Category: Protein complex]]
 
[[Category: Brown, D G.]]
[[Category: Brown, D G.]]
[[Category: Chwalinski, T.]]
[[Category: Chwalinski, T.]]
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[[Category: Wilson, W D.]]
[[Category: Wilson, W D.]]
[[Category: Zon, G.]]
[[Category: Zon, G.]]
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[[Category: a-dna]]
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[[Category: A-dna]]
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[[Category: double helix]]
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[[Category: Double helix]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:26:05 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:46:02 2008''
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Revision as of 15:26, 3 May 2008

Image:295d.jpg

Template:STRUCTURE 295d

CRYSTAL AND SOLUTION STRUCTURES OF THE OLIGONUCLEOTIDE D(ATGCGCAT)2: A COMBINED X-RAY AND NMR STUDY


Overview

A combined crystal-structure determination and NMR analysis of the octanucleotide d(ATGCGCAT)2 is reported. The X-ray analysis shows that the structure is A-form duplex in crystal state. The NMR study shows that in solution this sequence is B-type. The conformational results from each technique are presented in detail. The implications of these findings in terms of conformational flexibility and ligand binding are discussed.

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystal and solution structures of the oligonucleotide d(ATGCGCAT)2: a combined X-ray and NMR study., Clark GR, Brown DG, Sanderson MR, Chwalinski T, Neidle S, Veal JM, Jones RL, Wilson WD, Zon G, Garman E, et al., Nucleic Acids Res. 1990 Sep 25;18(18):5521-8. PMID:2216724 Page seeded by OCA on Sat May 3 18:26:05 2008

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