2a6k

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[[Image:2a6k.gif|left|200px]]
[[Image:2a6k.gif|left|200px]]
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{{Structure
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|PDB= 2a6k |SIZE=350|CAPTION= <scene name='initialview01'>2a6k</scene>, resolution 3.0&Aring;
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The line below this paragraph, containing "STRUCTURE_2a6k", creates the "Structure Box" on the page.
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|SITE=
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{{STRUCTURE_2a6k| PDB=2a6k | SCENE= }}
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|RELATEDENTRY=[[2a6d|2A6D]], [[2a6i|2A6I]], [[2a6j|2A6J]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2a6k FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2a6k OCA], [http://www.ebi.ac.uk/pdbsum/2a6k PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2a6k RCSB]</span>
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'''Crystal Structure Analysis of the germline antibody 36-65 Fab in complex with the dodecapeptide SLGDNLTNHNLR'''
'''Crystal Structure Analysis of the germline antibody 36-65 Fab in complex with the dodecapeptide SLGDNLTNHNLR'''
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==About this Structure==
==About this Structure==
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2A6K is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mus_musculus Mus musculus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A6K OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2A6K OCA].
==Reference==
==Reference==
Multiple paths to multispecificity., Mariuzza RA, Immunity. 2006 Apr;24(4):359-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16618592 16618592]
Multiple paths to multispecificity., Mariuzza RA, Immunity. 2006 Apr;24(4):359-61. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16618592 16618592]
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[[Category: Mus musculus]]
 
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[[Category: Protein complex]]
 
[[Category: Agarwal, A.]]
[[Category: Agarwal, A.]]
[[Category: Manivel, V.]]
[[Category: Manivel, V.]]
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[[Category: Salunke, D M.]]
[[Category: Salunke, D M.]]
[[Category: Sethi, D K.]]
[[Category: Sethi, D K.]]
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[[Category: fab-peptide complex]]
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[[Category: Fab-peptide complex]]
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[[Category: immunoglobulin fold]]
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[[Category: Immunoglobulin fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:40:15 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:48:29 2008''
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Revision as of 15:40, 3 May 2008

Template:STRUCTURE 2a6k

Crystal Structure Analysis of the germline antibody 36-65 Fab in complex with the dodecapeptide SLGDNLTNHNLR


Overview

The limited primary antibody repertoire uses multiple mechanisms to account for the large number of potential antigens. In this issue of Immunity, Sethi et al. (2006) describe a new means for expanding the antibody repertoire, whereby a single antibody isomer binds diverse antigens at different regions of the binding site.

About this Structure

Full crystallographic information is available from OCA.

Reference

Multiple paths to multispecificity., Mariuzza RA, Immunity. 2006 Apr;24(4):359-61. PMID:16618592 Page seeded by OCA on Sat May 3 18:40:15 2008

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