2afd
From Proteopedia
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'''Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence''' | '''Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence''' | ||
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[[Category: Wilson, I A.]] | [[Category: Wilson, I A.]] | ||
[[Category: Wuthrich, K.]] | [[Category: Wuthrich, K.]] | ||
| - | [[Category: | + | [[Category: Acyl carrier protein family]] |
| - | [[Category: | + | [[Category: Jcsg]] |
| - | [[Category: | + | [[Category: Joint center for structural genomic]] |
| - | [[Category: | + | [[Category: Protein structure initiative]] |
| - | [[Category: | + | [[Category: Psi]] |
| - | [[Category: | + | [[Category: Structural genomic]] |
| - | [[Category: | + | [[Category: Twisted antiparallel helical bundle]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 18:58:56 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 15:58, 3 May 2008
Solution Structure of Asl1650, an Acyl Carrier Protein from Anabaena sp. PCC 7120 with a Variant Phosphopantetheinylation-Site Sequence
Overview
Cyanobacteria, such as Anabaena, produce a variety of bioactive natural products via polyketide synthases (PKS), nonribosomal peptide synthetases (NRPS), and hybrid peptide/polyketide pathways. The protein Asl1650, which is a member of the acyl carrier protein family from the cyanobacterium Anabaena sp. PCC 7120, is encoded in a region of the Anabaena genome that is rich in PKS and NRPS genes. To gain new insight into the physiological role of acyl carriers in Anabaena, the solution structure of Asl1650 has been solved by NMR spectroscopy. The protein adopts a twisted antiparallel four-helix bundle fold, with a variant phosphopantetheine-attachment motif positioned at the start of the second helix. Structure comparisons with proteins from other organisms suggest a likely physiological function as a discrete peptidyl carrier protein.
About this Structure
2AFD is a Single protein structure of sequence from Anabaena sp.. Full crystallographic information is available from OCA.
Reference
Solution structure of Asl1650, an acyl carrier protein from Anabaena sp. PCC 7120 with a variant phosphopantetheinylation-site sequence., Johnson MA, Peti W, Herrmann T, Wilson IA, Wuthrich K, Protein Sci. 2006 May;15(5):1030-41. Epub 2006 Apr 5. PMID:16597827 Page seeded by OCA on Sat May 3 18:58:56 2008
Categories: Anabaena sp. | Single protein | Herrmann, T. | JCSG, Joint Center for Structural Genomics. | Johnson, M A. | Peti, W. | Wilson, I A. | Wuthrich, K. | Acyl carrier protein family | Jcsg | Joint center for structural genomic | Protein structure initiative | Psi | Structural genomic | Twisted antiparallel helical bundle
