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2afv

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[[Image:2afv.gif|left|200px]]
[[Image:2afv.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2afv |SIZE=350|CAPTION= <scene name='initialview01'>2afv</scene>, resolution 3.00&Aring;
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The line below this paragraph, containing "STRUCTURE_2afv", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=CL:CHLORIDE+ION'>CL</scene>, <scene name='pdbligand=P33:3,6,9,12,15,18-HEXAOXAICOSANE-1,20-DIOL'>P33</scene>, <scene name='pdbligand=P6G:HEXAETHYLENE+GLYCOL'>P6G</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Precorrin-8X_methylmutase Precorrin-8X methylmutase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=5.4.1.2 5.4.1.2] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_2afv| PDB=2afv | SCENE= }}
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|RELATEDENTRY=[[2afr|2AFR]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2afv FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2afv OCA], [http://www.ebi.ac.uk/pdbsum/2afv PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2afv RCSB]</span>
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}}
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'''The Crystal Structure of Putative Precorrin Isomerase CbiC in Cobalamin Biosynthesis'''
'''The Crystal Structure of Putative Precorrin Isomerase CbiC in Cobalamin Biosynthesis'''
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[[Category: Wei, Z.]]
[[Category: Wei, Z.]]
[[Category: Xue, Y.]]
[[Category: Xue, Y.]]
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[[Category: isomerase]]
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[[Category: Isomerase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 19:00:09 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:52:05 2008''
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Revision as of 16:00, 3 May 2008

Image:2afv.gif

Template:STRUCTURE 2afv

The Crystal Structure of Putative Precorrin Isomerase CbiC in Cobalamin Biosynthesis


Overview

The leptospira cbiC encodes the enzyme catalyzing the methyl rearrangement reaction of the cobalamin biosynthesis pathway. The protein has been cloned and overexpressed as a His-tagged recombinant protein in Escherichia coli. The crystal structures have been solved in two crystal forms (P4(2)2(1)2 and P3(1)21) diffracting to 3.0 and 2.3A resolution, respectively. The structures are similar to the precorrin-8x methyl mutase (CobH), an enzyme of the aerobic pathway to vitamin B12.

About this Structure

2AFV is a Single protein structure of sequence from Leptospira interrogans. Full crystallographic information is available from OCA.

Reference

The crystal structure of putative precorrin isomerase CbiC in cobalamin biosynthesis., Xue Y, Wei Z, Li X, Gong W, J Struct Biol. 2006 Mar;153(3):307-11. Epub 2005 Dec 27. PMID:16427313 Page seeded by OCA on Sat May 3 19:00:09 2008

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