2ao7

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[[Image:2ao7.gif|left|200px]]
[[Image:2ao7.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2ao7 |SIZE=350|CAPTION= <scene name='initialview01'>2ao7</scene>, resolution 2.9&Aring;
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The line below this paragraph, containing "STRUCTURE_2ao7", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/ADAM10_endopeptidase ADAM10 endopeptidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.24.81 3.4.24.81] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= ADAM10, MADM ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9913 Bos taurus])
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-->
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|DOMAIN=
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{{STRUCTURE_2ao7| PDB=2ao7 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ao7 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ao7 OCA], [http://www.ebi.ac.uk/pdbsum/2ao7 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ao7 RCSB]</span>
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}}
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'''Adam10 Disintegrin and cysteine- rich domain'''
'''Adam10 Disintegrin and cysteine- rich domain'''
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[[Category: Saha, N.]]
[[Category: Saha, N.]]
[[Category: Wimmer-Kleikamp, S H.]]
[[Category: Wimmer-Kleikamp, S H.]]
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[[Category: disintegrin]]
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[[Category: Disintegrin]]
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[[Category: extracellular]]
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[[Category: Extracellular]]
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[[Category: protease]]
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[[Category: Protease]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 19:16:48 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:55:13 2008''
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Revision as of 16:16, 3 May 2008

Image:2ao7.gif

Template:STRUCTURE 2ao7

Adam10 Disintegrin and cysteine- rich domain


Overview

Ephrin ligands presented on one cell surface associate with their receptors on the surface of a juxtaposed cell, often resulting in cell-cell repulsion. In this issue of Cell, Janes et al. (2005) show that the ephrin ligand can be proteolytically released from its membrane tether by a complex on the opposing cell composed of the ephrin receptor and an ADAM metalloprotease.

About this Structure

2AO7 is a Single protein structure of sequence from Bos taurus. Full crystallographic information is available from OCA.

Reference

ADAM and Eph: how Ephrin-signaling cells become detached., Mancia F, Shapiro L, Cell. 2005 Oct 21;123(2):185-7. PMID:16239135 Page seeded by OCA on Sat May 3 19:16:48 2008

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OCA

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