2ate

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[[Image:2ate.gif|left|200px]]
[[Image:2ate.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2ate |SIZE=350|CAPTION= <scene name='initialview01'>2ate</scene>, resolution 1.80&Aring;
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The line below this paragraph, containing "STRUCTURE_2ate", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=MSE:SELENOMETHIONINE'>MSE</scene>, <scene name='pdbligand=NIA:((2R,3S,4R,5R)-5-(5-AMINO-4-NITRO-1H-IMIDAZOL-1-YL)-3,4-DIHYDROXYTETRAHYDROFURAN-2-YL)METHYL+DIHYDROGEN+PHOSPHATE'>NIA</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Phosphoribosylaminoimidazole_carboxylase Phosphoribosylaminoimidazole carboxylase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.1.1.21 4.1.1.21] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= purE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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-->
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|DOMAIN=
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{{STRUCTURE_2ate| PDB=2ate | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2ate FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2ate OCA], [http://www.ebi.ac.uk/pdbsum/2ate PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2ate RCSB]</span>
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}}
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'''Structure of the complex of PurE with NitroAIR'''
'''Structure of the complex of PurE with NitroAIR'''
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[[Category: Stubbe, J.]]
[[Category: Stubbe, J.]]
[[Category: Zaugg, J B.]]
[[Category: Zaugg, J B.]]
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[[Category: nitroair complex]]
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[[Category: Nitroair complex]]
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[[Category: pure]]
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[[Category: Pure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 19:27:09 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 01:57:02 2008''
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Revision as of 16:27, 3 May 2008

Image:2ate.gif

Template:STRUCTURE 2ate

Structure of the complex of PurE with NitroAIR


Overview

Structural studies, sequence alignments, and biochemistry have provided new insights into the evolution of the purine biosynthetic pathway. The importance of chemistry, the binding of ribose 5-phosphate (common to all purine biosynthetic intermediates), and transient protein-protein interactions in channeling of chemically unstable intermediates have all been examined in the past few years.

About this Structure

2ATE is a Single protein structure of sequence from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Modular evolution of the purine biosynthetic pathway., Kappock TJ, Ealick SE, Stubbe J, Curr Opin Chem Biol. 2000 Oct;4(5):567-72. PMID:11006546 Page seeded by OCA on Sat May 3 19:27:09 2008

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OCA

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