2bsg
From Proteopedia
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[[Image:2bsg.gif|left|200px]] | [[Image:2bsg.gif|left|200px]] | ||
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'''THE MODELED STRUCTURE OF FIBRITIN (GPWAC) OF BACTERIOPHAGE T4 BASED ON CRYO-EM RECONSTRUCTION OF THE EXTENDED TAIL OF BACTERIOPHAGE T4''' | '''THE MODELED STRUCTURE OF FIBRITIN (GPWAC) OF BACTERIOPHAGE T4 BASED ON CRYO-EM RECONSTRUCTION OF THE EXTENDED TAIL OF BACTERIOPHAGE T4''' | ||
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[[Category: Mesyanzhinov, V V.]] | [[Category: Mesyanzhinov, V V.]] | ||
[[Category: Rossmann, M G.]] | [[Category: Rossmann, M G.]] | ||
- | [[Category: | + | [[Category: Attachment protein]] |
- | [[Category: | + | [[Category: Bacteriophage assembly]] |
- | [[Category: | + | [[Category: Bacteriophage t4]] |
- | [[Category: | + | [[Category: Chaperone]] |
- | [[Category: | + | [[Category: Coiled coil]] |
- | [[Category: | + | [[Category: Fibritin]] |
- | [[Category: | + | [[Category: Structural protein]] |
- | [[Category: | + | [[Category: Viral protein]] |
- | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 20:44:13 2008'' | |
- | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + |
Revision as of 17:44, 3 May 2008
THE MODELED STRUCTURE OF FIBRITIN (GPWAC) OF BACTERIOPHAGE T4 BASED ON CRYO-EM RECONSTRUCTION OF THE EXTENDED TAIL OF BACTERIOPHAGE T4
Overview
Bacteriophage T4 and related viruses have a contractile tail that serves as an efficient mechanical device for infecting bacteria. A three-dimensional cryo-EM reconstruction of the mature T4 tail assembly at 15-A resolution shows the hexagonal dome-shaped baseplate, the extended contractile sheath, the long tail fibers attached to the baseplate and the collar formed by six whiskers that interact with the long tail fibers. Comparison with the structure of the contracted tail shows that tail contraction is associated with a substantial rearrangement of the domains within the sheath protein and results in shortening of the sheath to about one-third of its original length. During contraction, the tail tube extends beneath the baseplate by about one-half of its total length and rotates by 345 degrees , allowing it to cross the host's periplasmic space.
About this Structure
2BSG is a Single protein structure of sequence from Enterobacteria phage t4. Full crystallographic information is available from OCA.
Reference
The tail structure of bacteriophage T4 and its mechanism of contraction., Kostyuchenko VA, Chipman PR, Leiman PG, Arisaka F, Mesyanzhinov VV, Rossmann MG, Nat Struct Mol Biol. 2005 Sep;12(9):810-3. Epub 2005 Aug 14. PMID:16116440 Page seeded by OCA on Sat May 3 20:44:13 2008