2c0x

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[[Image:2c0x.gif|left|200px]]
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{{Structure
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2c0x FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2c0x OCA], [http://www.ebi.ac.uk/pdbsum/2c0x PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2c0x RCSB]</span>
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'''MOLECULAR STRUCTURE OF FD FILAMENTOUS BACTERIOPHAGE REFINED WITH RESPECT TO X-RAY FIBRE DIFFRACTION AND SOLID-STATE NMR DATA'''
'''MOLECULAR STRUCTURE OF FD FILAMENTOUS BACTERIOPHAGE REFINED WITH RESPECT TO X-RAY FIBRE DIFFRACTION AND SOLID-STATE NMR DATA'''
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[[Category: Symmons, M F.]]
[[Category: Symmons, M F.]]
[[Category: Welsh, L C.]]
[[Category: Welsh, L C.]]
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[[Category: alpha-helix]]
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[[Category: Alpha-helix]]
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[[Category: capsid protein]]
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[[Category: Capsid protein]]
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[[Category: filamentous bacteriophage]]
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[[Category: Filamentous bacteriophage]]
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[[Category: helical virus]]
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[[Category: Helical virus]]
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[[Category: membrane protein]]
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[[Category: Membrane protein]]
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[[Category: structural protein]]
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[[Category: Structural protein]]
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[[Category: transmembrane]]
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[[Category: Transmembrane]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sat May 3 21:04:37 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:14:39 2008''
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Revision as of 18:04, 3 May 2008

Template:STRUCTURE 2c0x

MOLECULAR STRUCTURE OF FD FILAMENTOUS BACTERIOPHAGE REFINED WITH RESPECT TO X-RAY FIBRE DIFFRACTION AND SOLID-STATE NMR DATA


Overview

Filamentous bacteriophage (Inovirus) is a simple and well-characterized model system. The phage particle, or virion, is about 60 angstroms in diameter and several thousand angstrom units long. The virions are assembled at the bacterial membrane as they extrude out of the host without killing it, an example of specific transport of nucleoprotein assemblages across membranes. The Ff group (fd, f1 and M13) has been especially widely studied. Models of virion assembly have been proposed based on a molecular model of the fd virion derived by X-ray fibre diffraction. A somewhat different model of the fd virion using solid-state NMR data has been proposed, not consistent with these models of assembly nor with the X-ray diffraction data. Here we show that reinterpreted NMR data are also consistent with the model derived from X-ray fibre diffraction studies, and discuss models of virion assembly.

About this Structure

2C0X is a Single protein structure of sequence from Enterobacteria phage fd. Full crystallographic information is available from OCA.

Reference

Molecular structure of fd (f1, M13) filamentous bacteriophage refined with respect to X-ray fibre diffraction and solid-state NMR data supports specific models of phage assembly at the bacterial membrane., Marvin DA, Welsh LC, Symmons MF, Scott WR, Straus SK, J Mol Biol. 2006 Jan 13;355(2):294-309. Epub 2005 Nov 8. PMID:16300790 Page seeded by OCA on Sat May 3 21:04:37 2008

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