2dc3

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[[Image:2dc3.gif|left|200px]]
[[Image:2dc3.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2dc3 |SIZE=350|CAPTION= <scene name='initialview01'>2dc3</scene>, resolution 1.68&Aring;
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The line below this paragraph, containing "STRUCTURE_2dc3", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND= <scene name='pdbligand=ACY:ACETIC+ACID'>ACY</scene>, <scene name='pdbligand=HEM:PROTOPORPHYRIN+IX+CONTAINING+FE'>HEM</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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|GENE= CYGB ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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|DOMAIN=
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{{STRUCTURE_2dc3| PDB=2dc3 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2dc3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2dc3 OCA], [http://www.ebi.ac.uk/pdbsum/2dc3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2dc3 RCSB]</span>
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'''Crystal structure of human cytoglobin at 1.68 angstroms resolution'''
'''Crystal structure of human cytoglobin at 1.68 angstroms resolution'''
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[[Category: Sugimoto, H.]]
[[Category: Sugimoto, H.]]
[[Category: Yoshizato, K.]]
[[Category: Yoshizato, K.]]
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[[Category: cytoglobin]]
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[[Category: Cytoglobin]]
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[[Category: heme]]
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[[Category: Heme]]
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[[Category: myoglobin]]
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[[Category: Myoglobin]]
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[[Category: oxygen storage]]
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[[Category: Oxygen storage]]
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[[Category: oxygen transport]]
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[[Category: Oxygen transport]]
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[[Category: riken structural genomics/proteomics initiative]]
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[[Category: Riken structural genomics/proteomics initiative]]
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[[Category: rsgi]]
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[[Category: Rsgi]]
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[[Category: structural genomic]]
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[[Category: Structural genomic]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 00:08:52 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:32:41 2008''
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Revision as of 21:08, 3 May 2008

Image:2dc3.gif

Template:STRUCTURE 2dc3

Crystal structure of human cytoglobin at 1.68 angstroms resolution


Overview

Cytoglobin (Cgb) is a recently discovered member of the vertebrate haem-containing globin family. The structure of a new crystal form of wild-type human Cgb (space group C2) was determined at a resolution of 1.68 Angstrom. The results show the presence of an additional helix in the N-terminal residues (4-20) prior to the A helix and an ordered loop structure in the C-terminal region (168-188), while these extended peptides were invisible owing to disorder in the previously reported structures using a P3(2)21 crystal at a resolution of 2.4 Angstrom. A detailed comparison of the two crystal structures shows differences in the conformation of the residues (i.e. Arg84) in the haem environment owing to a different dimeric arrangement.

About this Structure

2DC3 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

High-resolution structure of human cytoglobin: identification of extra N- and C-termini and a new dimerization mode., Makino M, Sugimoto H, Sawai H, Kawada N, Yoshizato K, Shiro Y, Acta Crystallogr D Biol Crystallogr. 2006 Jun;62(Pt 6):671-7. Epub 2006, May 12. PMID:16699195 Page seeded by OCA on Sun May 4 00:08:52 2008

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