2e40

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[[Image:2e40.gif|left|200px]]
[[Image:2e40.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2e40 |SIZE=350|CAPTION= <scene name='initialview01'>2e40</scene>, resolution 1.90&Aring;
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The line below this paragraph, containing "STRUCTURE_2e40", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=LGC:(3S,4R,5R,6S)-3,4,5-TRIHYDROXY-6-(HYDROXYMETHYL)TETRAHYDRO-2H-PYRAN-2-ONE'>LGC</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Beta-glucosidase Beta-glucosidase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.2.1.21 3.2.1.21] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= bgl1A ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=5306 Phanerochaete chrysosporium])
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-->
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|DOMAIN=
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{{STRUCTURE_2e40| PDB=2e40 | SCENE= }}
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|RELATEDENTRY=[[2e3z|2E3Z]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2e40 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2e40 OCA], [http://www.ebi.ac.uk/pdbsum/2e40 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2e40 RCSB]</span>
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}}
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'''Crystal structure of intracellular family 1 beta-glucosidase BGL1A from the basidiomycete Phanerochaete chrysosporium in complex with gluconolactone'''
'''Crystal structure of intracellular family 1 beta-glucosidase BGL1A from the basidiomycete Phanerochaete chrysosporium in complex with gluconolactone'''
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[[Category: Samejima, M.]]
[[Category: Samejima, M.]]
[[Category: Tsukada, T.]]
[[Category: Tsukada, T.]]
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[[Category: clan gh-a]]
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[[Category: Clan gh-a]]
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[[Category: glycoside hydrolase family 1]]
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[[Category: Glycoside hydrolase family 1]]
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[[Category: national project on protein structural and functional analyse]]
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[[Category: National project on protein structural and functional analyse]]
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[[Category: nppsfa]]
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[[Category: Nppsfa]]
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[[Category: structural genomic]]
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[[Category: Structural genomic]]
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[[Category: tim barrel]]
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[[Category: Tim barrel]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 01:52:41 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:43:27 2008''
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Revision as of 22:52, 3 May 2008

Image:2e40.gif

Template:STRUCTURE 2e40

Crystal structure of intracellular family 1 beta-glucosidase BGL1A from the basidiomycete Phanerochaete chrysosporium in complex with gluconolactone


Overview

The white-rot fungus Phanerochaete chrysosporium has two intracellular beta-glucosidases (BGL1A and BGL1B) belonging to glycoside hydrolase (GH) family 1. BGL1B effectively hydrolyzes cellobiose and cellobionolactone, but BGL1A does not. We have determined the crystal structure of BGL1A in substrate-free and gluconolactone complexed forms. The overall structure and the characteristic of subsite -1 (glycone site) were similar to those of other known GH1 enzymes. The loop regions covering on the (beta/alpha)(8) barrel was significantly deviated, and they form a unique subsite +1 (aglycone site) of BGL1A.

About this Structure

2E40 is a Single protein structure of sequence from Phanerochaete chrysosporium. Full crystallographic information is available from OCA.

Reference

Crystal structure of intracellular family 1 beta-glucosidase BGL1A from the basidiomycete Phanerochaete chrysosporium., Nijikken Y, Tsukada T, Igarashi K, Samejima M, Wakagi T, Shoun H, Fushinobu S, FEBS Lett. 2007 Apr 3;581(7):1514-20. Epub 2007 Mar 13. PMID:17376440 Page seeded by OCA on Sun May 4 01:52:41 2008

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