2f87

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[[Image:2f87.gif|left|200px]]
[[Image:2f87.gif|left|200px]]
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{{Structure
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|PDB= 2f87 |SIZE=350|CAPTION= <scene name='initialview01'>2f87</scene>
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The line below this paragraph, containing "STRUCTURE_2f87", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
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{{STRUCTURE_2f87| PDB=2f87 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2f87 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2f87 OCA], [http://www.ebi.ac.uk/pdbsum/2f87 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2f87 RCSB]</span>
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'''Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus'''
'''Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus'''
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==About this Structure==
==About this Structure==
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2F87 is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F87 OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2F87 OCA].
==Reference==
==Reference==
Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus., Okada K, Takahashi M, Sakamoto T, Kawai G, Nakamura K, Kanai A, Nucleosides Nucleotides Nucleic Acids. 2006;25(4-6):383-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16838833 16838833]
Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus., Okada K, Takahashi M, Sakamoto T, Kawai G, Nakamura K, Kanai A, Nucleosides Nucleotides Nucleic Acids. 2006;25(4-6):383-95. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16838833 16838833]
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[[Category: Protein complex]]
 
[[Category: Kanai, A.]]
[[Category: Kanai, A.]]
[[Category: Kawai, G]]
[[Category: Kawai, G]]
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[[Category: Sakamoto, T.]]
[[Category: Sakamoto, T.]]
[[Category: Takahashi, M.]]
[[Category: Takahashi, M.]]
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[[Category: gnrr]]
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[[Category: Gnrr]]
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[[Category: rna]]
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[[Category: Rna]]
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[[Category: srp]]
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[[Category: Srp]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 03:34:44 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 02:59:14 2008''
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Revision as of 00:34, 4 May 2008

Image:2f87.gif

Template:STRUCTURE 2f87

Solution structure of a GAAG tetraloop in SRP RNA from Pyrococcus furiosus


Overview

The NMR structure of a 12-mer RNA derived from the helix 6 of SRP RNA from Pyrococcus furiosus, whose loop-closing base pair is U.G, was determined, and the structural and thermodynamic properties of the RNA were compared with those of a mutant RNA with the C:G closing base pair. Although the structures of the two RNAs are similar to each other and adopt the GNRR motif the conformational stabilities are significantly different to each other It was suggested that weaker stacking interaction of the GAAG loop with the U:G closing base pair in 12-mer RNA causes the lower conformational stability.

About this Structure

Full crystallographic information is available from OCA.

Reference

Solution structure of a GAAG tetraloop in helix 6 of SRP RNA from Pyrococcus furiosus., Okada K, Takahashi M, Sakamoto T, Kawai G, Nakamura K, Kanai A, Nucleosides Nucleotides Nucleic Acids. 2006;25(4-6):383-95. PMID:16838833 Page seeded by OCA on Sun May 4 03:34:44 2008

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