2fji

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[[Image:2fji.gif|left|200px]]
[[Image:2fji.gif|left|200px]]
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{{Structure
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The line below this paragraph, containing "STRUCTURE_2fji", creates the "Structure Box" on the page.
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|SITE=
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|GENE= SEC6 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
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{{STRUCTURE_2fji| PDB=2fji | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fji FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fji OCA], [http://www.ebi.ac.uk/pdbsum/2fji PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2fji RCSB]</span>
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'''Crystal structure of the C-terminal domain of the exocyst subunit Sec6p'''
'''Crystal structure of the C-terminal domain of the exocyst subunit Sec6p'''
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[[Category: Munson, M.]]
[[Category: Munson, M.]]
[[Category: Sivaram, M V.]]
[[Category: Sivaram, M V.]]
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[[Category: exocyst complex]]
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[[Category: Exocyst complex]]
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[[Category: exocytosis]]
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[[Category: Exocytosis]]
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[[Category: tandem helical bundle]]
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[[Category: Tandem helical bundle]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 03:58:20 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:03:38 2008''
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Revision as of 00:58, 4 May 2008

Image:2fji.gif

Template:STRUCTURE 2fji

Crystal structure of the C-terminal domain of the exocyst subunit Sec6p


Overview

The exocyst is a conserved protein complex essential for trafficking secretory vesicles to the plasma membrane. The structure of the C-terminal domain of the exocyst subunit Sec6p reveals multiple helical bundles, which are structurally and topologically similar to Exo70p and the C-terminal domains of Exo84p and Sec15, despite <10% sequence identity. The helical bundles appear to be evolutionarily related molecular scaffolds that have diverged to create functionally distinct exocyst proteins.

About this Structure

2FJI is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

The structure of the exocyst subunit Sec6p defines a conserved architecture with diverse roles., Sivaram MV, Furgason ML, Brewer DN, Munson M, Nat Struct Mol Biol. 2006 Jun;13(6):555-6. Epub 2006 May 14. PMID:16699513 Page seeded by OCA on Sun May 4 03:58:20 2008

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