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2fji
From Proteopedia
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[[Image:2fji.gif|left|200px]] | [[Image:2fji.gif|left|200px]] | ||
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'''Crystal structure of the C-terminal domain of the exocyst subunit Sec6p''' | '''Crystal structure of the C-terminal domain of the exocyst subunit Sec6p''' | ||
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[[Category: Munson, M.]] | [[Category: Munson, M.]] | ||
[[Category: Sivaram, M V.]] | [[Category: Sivaram, M V.]] | ||
| - | [[Category: | + | [[Category: Exocyst complex]] |
| - | [[Category: | + | [[Category: Exocytosis]] |
| - | [[Category: | + | [[Category: Tandem helical bundle]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 03:58:20 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 00:58, 4 May 2008
Crystal structure of the C-terminal domain of the exocyst subunit Sec6p
Overview
The exocyst is a conserved protein complex essential for trafficking secretory vesicles to the plasma membrane. The structure of the C-terminal domain of the exocyst subunit Sec6p reveals multiple helical bundles, which are structurally and topologically similar to Exo70p and the C-terminal domains of Exo84p and Sec15, despite <10% sequence identity. The helical bundles appear to be evolutionarily related molecular scaffolds that have diverged to create functionally distinct exocyst proteins.
About this Structure
2FJI is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.
Reference
The structure of the exocyst subunit Sec6p defines a conserved architecture with diverse roles., Sivaram MV, Furgason ML, Brewer DN, Munson M, Nat Struct Mol Biol. 2006 Jun;13(6):555-6. Epub 2006 May 14. PMID:16699513 Page seeded by OCA on Sun May 4 03:58:20 2008
