2flr

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[[Image:2flr.gif|left|200px]]
[[Image:2flr.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2flr |SIZE=350|CAPTION= <scene name='initialview01'>2flr</scene>, resolution 2.35&Aring;
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The line below this paragraph, containing "STRUCTURE_2flr", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=7NH:[2&#39;-HYDROXY-3&#39;-(1H-PYRROLO[3,2-C]PYRIDIN-2-YL)-BIPHENYL-3-YLMETHYL]-UREA'>7NH</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Coagulation_factor_VIIa Coagulation factor VIIa], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.4.21.21 3.4.21.21] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= F7 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), F3 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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-->
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|DOMAIN=
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{{STRUCTURE_2flr| PDB=2flr | SCENE= }}
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|RELATEDENTRY=[[2flb|2FLB]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2flr FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2flr OCA], [http://www.ebi.ac.uk/pdbsum/2flr PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2flr RCSB]</span>
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}}
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'''Novel 5-Azaindole Factor VIIa Inhibitors'''
'''Novel 5-Azaindole Factor VIIa Inhibitors'''
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[[Category: Yu, C.]]
[[Category: Yu, C.]]
[[Category: 5-azaindole inhibitor]]
[[Category: 5-azaindole inhibitor]]
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[[Category: s1 site]]
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[[Category: S1 site]]
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[[Category: short hydrogen bond]]
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[[Category: Short hydrogen bond]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 04:02:35 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:04:30 2008''
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Revision as of 01:02, 4 May 2008

Image:2flr.gif

Template:STRUCTURE 2flr

Novel 5-Azaindole Factor VIIa Inhibitors


Contents

Overview

The discovery and development of 5-azaindole factor VIIa inhibitors will be described.

Disease

Known disease associated with this structure: Factor VII deficiency OMIM:[227500], Myocardial infarction, decreased susceptibility to OMIM:[227500]

About this Structure

2FLR is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Novel 5-azaindole factor VIIa inhibitors., Riggs JR, Hu H, Kolesnikov A, Leahy EM, Wesson KE, Shrader WD, Vijaykumar D, Wahl TA, Tong Z, Sprengeler PA, Green MJ, Yu C, Katz BA, Sanford E, Nguyen M, Cabuslay R, Young WB, Bioorg Med Chem Lett. 2006 Jun 15;16(12):3197-200. Epub 2006 Apr 18. PMID:16621549 Page seeded by OCA on Sun May 4 04:02:35 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

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