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2fw3

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[[Image:2fw3.gif|left|200px]]
[[Image:2fw3.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2fw3 |SIZE=350|CAPTION= <scene name='initialview01'>2fw3</scene>, resolution 2.50&Aring;
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The line below this paragraph, containing "STRUCTURE_2fw3", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=BUI:(3R)-3-{[(TETRADECYLAMINO)CARBONYL]AMINO}-4-(TRIMETHYLAMMONIO)BUTANOATE'>BUI</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Carnitine_O-palmitoyltransferase Carnitine O-palmitoyltransferase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.3.1.21 2.3.1.21] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE=
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-->
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|DOMAIN=
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{{STRUCTURE_2fw3| PDB=2fw3 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2fw3 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2fw3 OCA], [http://www.ebi.ac.uk/pdbsum/2fw3 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2fw3 RCSB]</span>
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}}
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'''Crystal structure of rat carnitine palmitoyltransferase 2 in complex with antidiabetic drug ST1326'''
'''Crystal structure of rat carnitine palmitoyltransferase 2 in complex with antidiabetic drug ST1326'''
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[[Category: Stihle, M.]]
[[Category: Stihle, M.]]
[[Category: Thoma, R.]]
[[Category: Thoma, R.]]
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[[Category: central six-stranded beta-sheet]]
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[[Category: Central six-stranded beta-sheet]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 04:22:29 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:08:24 2008''
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Revision as of 01:22, 4 May 2008

Image:2fw3.gif

Template:STRUCTURE 2fw3

Crystal structure of rat carnitine palmitoyltransferase 2 in complex with antidiabetic drug ST1326


Overview

Carnitine palmitoyltransferases (CPTs) are part of the enzymatic system that imports fatty acids into mitochondria. The crystal structure of rat CPT-2 by Rufer et al. (2006) (this issue of Structure) reveals a Y-shaped tunnel for binding the CoA and acyl-carnitine substrates and a hydrophobic insert mediating membrane association.

About this Structure

2FW3 is a Single protein structure of sequence from Rattus norvegicus. Full crystallographic information is available from OCA.

Reference

A monotopic membrane protein goes solo., Mattevi A, Structure. 2006 Apr;14(4):628-9. PMID:16615901 Page seeded by OCA on Sun May 4 04:22:29 2008

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