2gej

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[[Image:2gej.jpg|left|200px]]
[[Image:2gej.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 2gej |SIZE=350|CAPTION= <scene name='initialview01'>2gej</scene>, resolution 2.600&Aring;
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The line below this paragraph, containing "STRUCTURE_2gej", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=GDD:GUANOSINE-5&#39;-DIPHOSPHATE-ALPHA-D-MANNOSE'>GDD</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE= PIMA ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=1772 Mycobacterium smegmatis])
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-->
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|DOMAIN=
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{{STRUCTURE_2gej| PDB=2gej | SCENE= }}
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|RELATEDENTRY=[[2gek|2GEK]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gej FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gej OCA], [http://www.ebi.ac.uk/pdbsum/2gej PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2gej RCSB]</span>
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}}
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'''Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP-Man'''
'''Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP-Man'''
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==About this Structure==
==About this Structure==
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2GEJ is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Mycobacterium_smegmatis Mycobacterium smegmatis]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GEJ OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GEJ OCA].
==Reference==
==Reference==
Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis., Guerin ME, Buschiazzo A, Kordulakova J, Jackson M, Alzari PM, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 May 1;61(Pt, 5):518-20. Epub 2005 Apr 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16511084 16511084]
Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis., Guerin ME, Buschiazzo A, Kordulakova J, Jackson M, Alzari PM, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 May 1;61(Pt, 5):518-20. Epub 2005 Apr 22. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/16511084 16511084]
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[[Category: Mycobacterium smegmatis]]
 
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[[Category: Protein complex]]
 
[[Category: Alzari, P M.]]
[[Category: Alzari, P M.]]
[[Category: Buschiazzo, A.]]
[[Category: Buschiazzo, A.]]
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[[Category: Jackson, M.]]
[[Category: Jackson, M.]]
[[Category: Kordulakova, J.]]
[[Category: Kordulakova, J.]]
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[[Category: binary complex,]]
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[[Category: Binary complex]]
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[[Category: gt4 glycosyltransferase]]
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[[Category: Gt4 glycosyltransferase]]
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[[Category: mannosyltransferase]]
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[[Category: Mannosyltransferase]]
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[[Category: rossmann fold]]
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[[Category: Rossmann fold]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 05:00:44 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:15:33 2008''
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Revision as of 02:00, 4 May 2008

Template:STRUCTURE 2gej

Crystal Structure of phosphatidylinositol mannosyltransferase (PimA) from Mycobacterium smegmatis in complex with GDP-Man


Overview

Phosphatidylinositol mannosyltransferase (PimA) is an essential enzyme for mycobacterial growth that catalyses the first mannosylation step in phosphatidyl-myo-inositol mannoside (PIM) biosynthesis. The enzyme belongs to the large GT4 family of glycosyltransferases, for which no structure is currently available. Recombinant purified PimA from Mycobacterium smegmatis has been crystallized in the presence of GDP and myo-inositol. The crystals belong to space group P2(1)2(1)2(1), with unit-cell parameters a = 37.2, b = 72.4, c = 138.2 A, and diffract to 2.4 A resolution.

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystallization and preliminary crystallographic analysis of PimA, an essential mannosyltransferase from Mycobacterium smegmatis., Guerin ME, Buschiazzo A, Kordulakova J, Jackson M, Alzari PM, Acta Crystallogr Sect F Struct Biol Cryst Commun. 2005 May 1;61(Pt, 5):518-20. Epub 2005 Apr 22. PMID:16511084 Page seeded by OCA on Sun May 4 05:00:44 2008

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