2gf1

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[[Image:2gf1.jpg|left|200px]]
[[Image:2gf1.jpg|left|200px]]
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{{Structure
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The line below this paragraph, containing "STRUCTURE_2gf1", creates the "Structure Box" on the page.
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{{STRUCTURE_2gf1| PDB=2gf1 | SCENE= }}
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|RELATEDENTRY=[[3gf1|3GF1]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gf1 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gf1 OCA], [http://www.ebi.ac.uk/pdbsum/2gf1 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2gf1 RCSB]</span>
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'''SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY'''
'''SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY'''
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[[Category: Cooke, R M.]]
[[Category: Cooke, R M.]]
[[Category: Harvey, T S.]]
[[Category: Harvey, T S.]]
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[[Category: growth factor]]
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[[Category: Growth factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 05:01:47 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:15:45 2008''
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Revision as of 02:01, 4 May 2008

Image:2gf1.jpg

Template:STRUCTURE 2gf1

SOLUTION STRUCTURE OF HUMAN INSULIN-LIKE GROWTH FACTOR 1: A NUCLEAR MAGNETIC RESONANCE AND RESTRAINED MOLECULAR DYNAMICS STUDY


Overview

The solution structure of human insulin-like growth factor 1 has been investigated with a combination of nuclear magnetic resonance and restrained molecular dynamics methods. The results show that the solution structure is similar to that of insulin, but minor differences exist. The regions homologous to insulin are well-defined, while the remainder of the molecule exhibits greater disorder. The resultant structures have been used to visualize the sites for interaction with a number of physiologically important proteins.

About this Structure

2GF1 is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Solution structure of human insulin-like growth factor 1: a nuclear magnetic resonance and restrained molecular dynamics study., Cooke RM, Harvey TS, Campbell ID, Biochemistry. 1991 Jun 4;30(22):5484-91. PMID:2036417 Page seeded by OCA on Sun May 4 05:01:47 2008

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