2gzl

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[[Image:2gzl.gif|left|200px]]
[[Image:2gzl.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2gzl |SIZE=350|CAPTION= <scene name='initialview01'>2gzl</scene>, resolution 2.50&Aring;
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The line below this paragraph, containing "STRUCTURE_2gzl", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=2AA:5&#39;-O-{[({[2-({[5-(DIMETHYLAMINO)NAPHTHALEN-1-YL]SULFONYL}AMINO)ETHYL]OXY}PHOSPHINATO)OXY]PHOSPHINATO}CYT'>2AA</scene>, <scene name='pdbligand=GPP:GERANYL+DIPHOSPHATE'>GPP</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/2-C-methyl-D-erythritol_2,4-cyclodiphosphate_synthase 2-C-methyl-D-erythritol 2,4-cyclodiphosphate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=4.6.1.12 4.6.1.12] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= ispF, mecS ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=562 Escherichia coli])
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-->
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|DOMAIN=
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{{STRUCTURE_2gzl| PDB=2gzl | SCENE= }}
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|RELATEDENTRY=[[1gx1|1GX1]], [[1knj|1KNJ]], [[1u3p|1U3P]], [[2amt|2AMT]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2gzl FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2gzl OCA], [http://www.ebi.ac.uk/pdbsum/2gzl PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2gzl RCSB]</span>
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}}
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'''Structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with a CDP derived fluorescent inhibitor'''
'''Structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with a CDP derived fluorescent inhibitor'''
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==About this Structure==
==About this Structure==
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2GZL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry 2AO4. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZL OCA].
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2GZL is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. This structure supersedes the now removed PDB entry [http://oca.weizmann.ac.il/oca-bin/send-pdb?obs=1&id=2ao4 2ao4]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2GZL OCA].
==Reference==
==Reference==
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[[Category: Rohdich, F.]]
[[Category: Rohdich, F.]]
[[Category: Wolfgang, E.]]
[[Category: Wolfgang, E.]]
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[[Category: isoprene biosynthesis]]
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[[Category: Isoprene biosynthesis]]
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[[Category: isoprenoid]]
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[[Category: Isoprenoid]]
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[[Category: lyase]]
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[[Category: Lyase]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 05:41:26 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:23:23 2008''
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Revision as of 02:41, 4 May 2008

Image:2gzl.gif

Template:STRUCTURE 2gzl

Structure of 2C-methyl-D-erythritol 2,4-clycodiphosphate synthase complexed with a CDP derived fluorescent inhibitor


About this Structure

2GZL is a Single protein structure of sequence from Escherichia coli. This structure supersedes the now removed PDB entry 2ao4. Full crystallographic information is available from OCA.

Reference

Fluorescent inhibitors for IspF, an enzyme in the non-mevalonate pathway for isoprenoid biosynthesis and a potential target for antimalarial therapy., Crane CM, Kaiser J, Ramsden NL, Lauw S, Rohdich F, Eisenreich W, Hunter WN, Bacher A, Diederich F, Angew Chem Int Ed Engl. 2006 Feb 6;45(7):1069-74. PMID:16392111 Page seeded by OCA on Sun May 4 05:41:26 2008

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