2hcy

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[[Image:2hcy.gif|left|200px]]
[[Image:2hcy.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2hcy |SIZE=350|CAPTION= <scene name='initialview01'>2hcy</scene>, resolution 2.44&Aring;
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The line below this paragraph, containing "STRUCTURE_2hcy", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=8ID:NICOTINAMIDE-8-IODO-ADENINE-DINUCLEOTIDE'>8ID</scene>, <scene name='pdbligand=ETF:TRIFLUOROETHANOL'>ETF</scene>, <scene name='pdbligand=ZN:ZINC+ION'>ZN</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Alcohol_dehydrogenase Alcohol dehydrogenase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=1.1.1.1 1.1.1.1] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= ADH1, ADC1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
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-->
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|DOMAIN=
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{{STRUCTURE_2hcy| PDB=2hcy | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hcy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hcy OCA], [http://www.ebi.ac.uk/pdbsum/2hcy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2hcy RCSB]</span>
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}}
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'''Yeast Alcohol Dehydrogenase I, Saccharomyces cerevisiae fermentative enzyme'''
'''Yeast Alcohol Dehydrogenase I, Saccharomyces cerevisiae fermentative enzyme'''
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[[Category: Ramaswamy, S.]]
[[Category: Ramaswamy, S.]]
[[Category: Savarimuthu, B R.]]
[[Category: Savarimuthu, B R.]]
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[[Category: intramolecular disulfide bond]]
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[[Category: Intramolecular disulfide bond]]
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[[Category: oxidoreductase]]
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[[Category: Oxidoreductase]]
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[[Category: tetramer of asymmetric dimer]]
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[[Category: Tetramer of asymmetric dimer]]
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[[Category: zinc coordination]]
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[[Category: Zinc coordination]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 06:08:05 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:28:37 2008''
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Revision as of 03:08, 4 May 2008

Image:2hcy.gif

Template:STRUCTURE 2hcy

Yeast Alcohol Dehydrogenase I, Saccharomyces cerevisiae fermentative enzyme


Overview

The cytoplasmic yeast alcohol dehydrogenase I crystallized at 5 degrees C as hexagonal plates or short columns in the presence of NAD+ and 2,2,2-trifluoroethanol, in sodium N-tris(hydroxymethyl)methyl-3-aminopropanesulfonate buffer at pH 8.2 to 8.6, using polyethylene glycol 4000 as precipitant. X-ray diffraction data to 3.2 A resolution show that the crystals are hexagonal in space group P622 with unit cell dimensions a = b = 147.9 A, c = 69.1 A. There is one subunit of the tetrameric enzyme per asymmetric unit, giving a packing density of 2.9 A3/Da.

About this Structure

2HCY is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Crystallization and preliminary crystallographic studies of Saccharomyces cerevisiae alcohol dehydrogenase I., Ramaswamy S, Kratzer DA, Hershey AD, Rogers PH, Arnone A, Eklund H, Plapp BV, J Mol Biol. 1994 Jan 14;235(2):777-9. PMID:8289298 Page seeded by OCA on Sun May 4 06:08:05 2008

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