2hlh

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
[[Image:2hlh.gif|left|200px]]
[[Image:2hlh.gif|left|200px]]
-
{{Structure
+
<!--
-
|PDB= 2hlh |SIZE=350|CAPTION= <scene name='initialview01'>2hlh</scene>, resolution 1.95&Aring;
+
The line below this paragraph, containing "STRUCTURE_2hlh", creates the "Structure Box" on the page.
-
|SITE= <scene name='pdbsite=AC1:Po4+Binding+Site+For+Residue+A+331'>AC1</scene>, <scene name='pdbsite=AC2:Po4+Binding+Site+For+Residue+A+332'>AC2</scene>, <scene name='pdbsite=AC3:Po4+Binding+Site+For+Residue+A+333'>AC3</scene> and <scene name='pdbsite=AC4:Po4+Binding+Site+For+Residue+A+334'>AC4</scene>
+
You may change the PDB parameter (which sets the PDB file loaded into the applet)
-
|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>
+
or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
-
|ACTIVITY=
+
or leave the SCENE parameter empty for the default display.
-
|GENE= nodZ ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=376 Bradyrhizobium sp.])
+
-->
-
|DOMAIN=
+
{{STRUCTURE_2hlh| PDB=2hlh | SCENE= }}
-
|RELATEDENTRY=[[2hhc|2hhc]]
+
-
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hlh FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hlh OCA], [http://www.ebi.ac.uk/pdbsum/2hlh PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2hlh RCSB]</span>
+
-
}}
+
'''Crystal structure of fucosyltransferase NodZ from Bradyrhizobium'''
'''Crystal structure of fucosyltransferase NodZ from Bradyrhizobium'''
Line 30: Line 27:
[[Category: Panjikar, S.]]
[[Category: Panjikar, S.]]
[[Category: Stepkowski, T.]]
[[Category: Stepkowski, T.]]
-
[[Category: fucosyltransferase]]
+
[[Category: Fucosyltransferase]]
-
[[Category: glycosyltransferase]]
+
[[Category: Glycosyltransferase]]
-
[[Category: nodulation]]
+
[[Category: Nodulation]]
-
[[Category: nodz]]
+
[[Category: Nodz]]
-
 
+
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 06:25:46 2008''
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:31:58 2008''
+

Revision as of 03:25, 4 May 2008

Image:2hlh.gif

Template:STRUCTURE 2hlh

Crystal structure of fucosyltransferase NodZ from Bradyrhizobium


Overview

The fucosyltransferase NodZ is involved in the biosynthesis of the nodulation factor in nitrogen-fixing symbiotic bacteria. It catalyzes alpha1,6 transfer of l-fucose from GDP-fucose to the reducing residue of the synthesized Nod oligosaccharide. We present the structure of the NodZ protein from Bradyrhizobium expressed in Escherichia coli and crystallized in the presence of phosphate ions in two crystal forms. The enzyme is arranged into two domains of nearly equal size. Although NodZ falls in one broad class (GT-B) with other two-domain glycosyltransferases, the topology of its domains deviates from the canonical Rossmann fold, with particularly high distortions in the N-terminal domain. Mutational data combined with structural and sequence alignments indicate residues of potential importance in GDP-fucose binding or in the catalytic mechanism. They are all clustered in three conserved sequence motifs located in the C-terminal domain.

About this Structure

2HLH is a Single protein structure of sequence from Bradyrhizobium sp.. Full crystallographic information is available from OCA.

Reference

High-resolution structure of NodZ fucosyltransferase involved in the biosynthesis of the nodulation factor., Brzezinski K, Stepkowski T, Panjikar S, Bujacz G, Jaskolski M, Acta Biochim Pol. 2007;54(3):537-49. Epub 2007 Aug 30. PMID:17762900 Page seeded by OCA on Sun May 4 06:25:46 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/2hlh"
Personal tools