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2huw

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[[Image:2huw.gif|left|200px]]
[[Image:2huw.gif|left|200px]]
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{{Structure
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<!--
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|PDB= 2huw |SIZE=350|CAPTION= <scene name='initialview01'>2huw</scene>, resolution 1.900&Aring;
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The line below this paragraph, containing "STRUCTURE_2huw", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=PO4:PHOSPHATE+ION'>PO4</scene>, <scene name='pdbligand=YVN:N-({(1R,2R,3S)-2-[(METHYLAMINO)CARBONYL]-3-[4-(PHOSPHONOOXY)PHENYL]CYCLOPROPYL}CARBONYL)-L-VALYL-L-ASPARTAMIDE'>YVN</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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or leave the SCENE parameter empty for the default display.
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|GENE= GRB2, ASH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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-->
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|DOMAIN=
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{{STRUCTURE_2huw| PDB=2huw | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2huw FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2huw OCA], [http://www.ebi.ac.uk/pdbsum/2huw PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2huw RCSB]</span>
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}}
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'''X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand'''
'''X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand'''
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[[Category: Benfield, A P.]]
[[Category: Benfield, A P.]]
[[Category: Martin, S F.]]
[[Category: Martin, S F.]]
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[[Category: contrained]]
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[[Category: Contrained]]
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[[Category: cylcopropane]]
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[[Category: Cylcopropane]]
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[[Category: grb2]]
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[[Category: Grb2]]
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[[Category: preorganization,]]
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[[Category: Preorganization]]
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[[Category: sh2]]
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[[Category: Sh2]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 06:44:28 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:35:49 2008''
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Revision as of 03:44, 4 May 2008

Image:2huw.gif

Template:STRUCTURE 2huw

X-ray crystal structure of the Grb2 SH2 domain complexed to a constrained and cyclopropane-derived ligand


About this Structure

2HUW is a Single protein structure of sequence from Homo sapiens. Full crystallographic information is available from OCA.

Reference

Ligand preorganization may be accompanied by entropic penalties in protein-ligand interactions., Benfield AP, Teresk MG, Plake HR, DeLorbe JE, Millspaugh LE, Martin SF, Angew Chem Int Ed Engl. 2006 Oct 20;45(41):6830-5. PMID:17001728 Page seeded by OCA on Sun May 4 06:44:28 2008

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OCA

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