2hvp

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[[Image:2hvp.gif|left|200px]]
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{{Structure
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2hvp FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2hvp OCA], [http://www.ebi.ac.uk/pdbsum/2hvp PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2hvp RCSB]</span>
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'''THREE-DIMENSIONAL STRUCTURE OF ASPARTYL PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS HIV-1'''
'''THREE-DIMENSIONAL STRUCTURE OF ASPARTYL PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS HIV-1'''
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[[Category: Navia, M A.]]
[[Category: Navia, M A.]]
[[Category: Springer, J P.]]
[[Category: Springer, J P.]]
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[[Category: hydrolase(acid proteinase)]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 06:46:12 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:36:02 2008''
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Revision as of 03:46, 4 May 2008

Image:2hvp.gif

Template:STRUCTURE 2hvp

THREE-DIMENSIONAL STRUCTURE OF ASPARTYL PROTEASE FROM HUMAN IMMUNODEFICIENCY VIRUS HIV-1


Overview

The crystal structure of the protease of the human immunodeficiency virus type (HIV-1), which releases structural proteins and enzymes from viral polyprotein products, has been determined to 3 A resolution. Large regions of the protease dimer, including the active site, have structural homology to the family of microbial aspartyl proteases. The structure suggests a mechanism for the autoproteolytic release of protease and a role in the control of virus maturation.

About this Structure

2HVP is a Single protein structure of sequence from Human immunodeficiency virus 1. Full crystallographic information is available from OCA.

Reference

Three-dimensional structure of aspartyl protease from human immunodeficiency virus HIV-1., Navia MA, Fitzgerald PM, McKeever BM, Leu CT, Heimbach JC, Herber WK, Sigal IS, Darke PL, Springer JP, Nature. 1989 Feb 16;337(6208):615-20. PMID:2645523 Page seeded by OCA on Sun May 4 06:46:12 2008

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