2q38

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(New page: 200px<br /> <applet load="2q38" size="450" color="white" frame="true" align="right" spinBox="true" caption="2q38, resolution 1.95&Aring;" /> '''Carbonic Anhydrase ...)
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Revision as of 21:22, 12 November 2007

Image:2q38.gif

2q38, resolution 1.95Å

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Carbonic Anhydrase II in complex with Saccharin at 1.95 Angstrom

Disease

Known disease associated with this structure: Osteopetrosis, autosomal recessive 3, with renal tubular acidosis OMIM:[611492]

About this Structure

2Q38 is a Single protein structure of sequence from Homo sapiens with ZN, HG, LSA, BEZ and GOL as ligands. Active as Carbonate dehydratase, with EC number 4.2.1.1 Full crystallographic information is available from OCA.

Reference

Saccharin inhibits carbonic anhydrases: possible explanation for its unpleasant metallic aftertaste., Kohler K, Hillebrecht A, Schulze Wischeler J, Innocenti A, Heine A, Supuran CT, Klebe G, Angew Chem Int Ed Engl. 2007;46(40):7697-9. PMID:17705204

Page seeded by OCA on Mon Nov 12 23:29:11 2007

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