2iub
From Proteopedia
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'''CRYSTAL STRUCTURE OF A DIVALENT METAL ION TRANSPORTER CORA AT 2.9 A RESOLUTION.''' | '''CRYSTAL STRUCTURE OF A DIVALENT METAL ION TRANSPORTER CORA AT 2.9 A RESOLUTION.''' | ||
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[[Category: Niegowski, D.]] | [[Category: Niegowski, D.]] | ||
[[Category: Nordlund, P.]] | [[Category: Nordlund, P.]] | ||
| - | [[Category: | + | [[Category: Cora]] |
| - | [[Category: | + | [[Category: Divalent cation]] |
| - | [[Category: | + | [[Category: Ion transporter]] |
| - | [[Category: | + | [[Category: Membrane protein]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 07:53:21 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 04:53, 4 May 2008
CRYSTAL STRUCTURE OF A DIVALENT METAL ION TRANSPORTER CORA AT 2.9 A RESOLUTION.
Overview
CorA family members are ubiquitously distributed transporters of divalent metal cations and are considered to be the primary Mg2+ transporter of Bacteria and Archaea. We have determined a 2.9 angstrom resolution structure of CorA from Thermotoga maritima that reveals a pentameric cone-shaped protein. Two potential regulatory metal binding sites are found in the N-terminal domain that bind both Mg2+ and Co2+. The structure of CorA supports an efflux system involving dehydration and rehydration of divalent metal ions potentially mediated by a ring of conserved aspartate residues at the cytoplasmic entrance and a carbonyl funnel at the periplasmic side of the pore.
About this Structure
2IUB is a Single protein structure of sequence from Thermotoga maritima. Full crystallographic information is available from OCA.
Reference
Crystal structure of a divalent metal ion transporter CorA at 2.9 angstrom resolution., Eshaghi S, Niegowski D, Kohl A, Martinez Molina D, Lesley SA, Nordlund P, Science. 2006 Jul 21;313(5785):354-7. PMID:16857941 Page seeded by OCA on Sun May 4 07:53:21 2008
