2j01

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[[Image:2j01.gif|left|200px]]
[[Image:2j01.gif|left|200px]]
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{{Structure
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|PDB= 2j01 |SIZE=350|CAPTION= <scene name='initialview01'>2j01</scene>, resolution 2.8&Aring;
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The line below this paragraph, containing "STRUCTURE_2j01", creates the "Structure Box" on the page.
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
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{{STRUCTURE_2j01| PDB=2j01 | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2j01 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2j01 OCA], [http://www.ebi.ac.uk/pdbsum/2j01 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2j01 RCSB]</span>
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'''STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH MRNA, TRNA AND PAROMOMYCIN (PART 2 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT FROM MOLECULE I.'''
'''STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH MRNA, TRNA AND PAROMOMYCIN (PART 2 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT FROM MOLECULE I.'''
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[[Category: Weir, J R.]]
[[Category: Weir, J R.]]
[[Category: Weixlbaumer, A.]]
[[Category: Weixlbaumer, A.]]
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[[Category: Mrna]]
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[[Category: paromomycin]]
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[[Category: Paromomycin]]
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[[Category: ribosome]]
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[[Category: Ribosome]]
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[[Category: translation]]
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[[Category: Translation]]
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[[Category: trna]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 08:08:45 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:51:07 2008''
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Revision as of 05:08, 4 May 2008

Image:2j01.gif

Template:STRUCTURE 2j01

STRUCTURE OF THE THERMUS THERMOPHILUS 70S RIBOSOME COMPLEXED WITH MRNA, TRNA AND PAROMOMYCIN (PART 2 OF 4). THIS FILE CONTAINS THE 50S SUBUNIT FROM MOLECULE I.


Overview

The crystal structure of the bacterial 70S ribosome refined to 2.8 angstrom resolution reveals atomic details of its interactions with messenger RNA (mRNA) and transfer RNA (tRNA). A metal ion stabilizes a kink in the mRNA that demarcates the boundary between A and P sites, which is potentially important to prevent slippage of mRNA. Metal ions also stabilize the intersubunit interface. The interactions of E-site tRNA with the 50S subunit have both similarities and differences compared to those in the archaeal ribosome. The structure also rationalizes much biochemical and genetic data on translation.

About this Structure

2J01 is a Protein complex structure of sequences from Thermus thermophilus. Full crystallographic information is available from OCA.

Reference

Structure of the 70S ribosome complexed with mRNA and tRNA., Selmer M, Dunham CM, Murphy FV 4th, Weixlbaumer A, Petry S, Kelley AC, Weir JR, Ramakrishnan V, Science. 2006 Sep 29;313(5795):1935-42. Epub 2006 Sep 7. PMID:16959973 Page seeded by OCA on Sun May 4 08:08:45 2008

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