2jh8

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[[Image:2jh8.gif|left|200px]]
[[Image:2jh8.gif|left|200px]]
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{{Structure
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|PDB= 2jh8 |SIZE=350|CAPTION= <scene name='initialview01'>2jh8</scene>, resolution 3.22&Aring;
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The line below this paragraph, containing "STRUCTURE_2jh8", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=AC1:Gun+Binding+Site+For+Chain+A'>AC1</scene>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=GUN:GUANINE'>GUN</scene>, <scene name='pdbligand=M7G:7N-METHYL-8-HYDROGUANOSINE-5&#39;-DIPHOSPHATE'>M7G</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY=
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|GENE=
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|DOMAIN=
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{{STRUCTURE_2jh8| PDB=2jh8 | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2jh8 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2jh8 OCA], [http://www.ebi.ac.uk/pdbsum/2jh8 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2jh8 RCSB]</span>
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}}
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'''THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE'''
'''THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE'''
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==Reference==
==Reference==
Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17417654 17417654]
Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17417654 17417654]
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[[Category: Bluetongue virus 10 (isolate usa)]]
 
[[Category: Single protein]]
[[Category: Single protein]]
[[Category: Grimes, J M.]]
[[Category: Grimes, J M.]]
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[[Category: Stuart, D I.]]
[[Category: Stuart, D I.]]
[[Category: Sutton, G.]]
[[Category: Sutton, G.]]
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[[Category: core protein]]
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[[Category: Core protein]]
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[[Category: guanylyltransferase]]
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[[Category: Guanylyltransferase]]
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[[Category: methyltransferase]]
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[[Category: Methyltransferase]]
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[[Category: viral capping enzyme]]
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[[Category: Viral capping enzyme]]
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[[Category: viral protein]]
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[[Category: Viral protein]]
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[[Category: virion protein]]
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[[Category: Virion protein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 08:54:56 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 03:58:09 2008''
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Revision as of 05:54, 4 May 2008

Image:2jh8.gif

Template:STRUCTURE 2jh8

THE STRUCTURE OF BLUETONGUE VIRUS VP4 REVEALS A MULTIFUNCTIONAL RNA-CAPPING PRODUCTION-LINE


Overview

Eukaryotic organisms cap the 5' ends of their messenger RNAs by a series of four chemical reactions. Some viruses achieve this using a single molecule; the crystal structure of such an enzyme from bluetongue virus reveals an elongated modular architecture that provides a scaffold for an assemblage of active sites, two contributed by a domain of novel structure.

About this Structure

2JH8 is a Single protein structure of sequence from Bluetongue virus 10 (isolate usa). Full crystallographic information is available from OCA.

Reference

Bluetongue virus VP4 is an RNA-capping assembly line., Sutton G, Grimes JM, Stuart DI, Roy P, Nat Struct Mol Biol. 2007 May;14(5):449-51. Epub 2007 Apr 8. PMID:17417654 Page seeded by OCA on Sun May 4 08:54:56 2008

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OCA

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