1ikd
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(New page: 200px<br /> <applet load="1ikd" size="450" color="white" frame="true" align="right" spinBox="true" caption="1ikd" /> '''ACCEPTOR STEM, NMR, 30 STRUCTURES'''<br /> ...)
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Revision as of 17:05, 29 October 2007
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ACCEPTOR STEM, NMR, 30 STRUCTURES
Overview
The fidelity of translation of the genetic code depends on accurate tRNA, aminoacylation by cognate aminoacyl-tRNA synthetases. Thus, each tRNA has, specificity not only for codon recognition, but also for amino acid, identity; this aminoacylation specificity is referred to as tRNA identity., The primary determinant of the acceptor identity of Escherichia coli, tRNAAlais a wobble G3.U70 pair within the acceptor stem. Despite extensive, biochemical and genetic data, the mechanism by which the G3.U70 pair marks, the acceptor end of tRNAAla for aminoacylation with alanine has not been, clarified at the molecular level. The solution structure of a microhelix, derived from the tRNAAla acceptor end has been determined at high, precision using a very extensive set of experimental constraints, ... [(full description)]
About this Structure
1IKD is a [Protein complex] structure of sequences from [[1]]. Full crystallographic information is available from [OCA].
Reference
Structure of the acceptor stem of Escherichia coli tRNA Ala: role of the G3.U70 base pair in synthetase recognition., Ramos A, Varani G, Nucleic Acids Res. 1997 Jun 1;25(11):2083-90. PMID:9153306
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