2q62

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[[Image:2q62.jpg|left|200px]]
[[Image:2q62.jpg|left|200px]]
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{{Structure
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|PDB= 2q62 |SIZE=350|CAPTION= <scene name='initialview01'>2q62</scene>, resolution 1.800&Aring;
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The line below this paragraph, containing "STRUCTURE_2q62", creates the "Structure Box" on the page.
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|GENE= arsH ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=382 Sinorhizobium meliloti])
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{{STRUCTURE_2q62| PDB=2q62 | SCENE= }}
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2q62 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2q62 OCA], [http://www.ebi.ac.uk/pdbsum/2q62 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2q62 RCSB]</span>
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'''Crystal Structure of ArsH from Sinorhizobium meliloti'''
'''Crystal Structure of ArsH from Sinorhizobium meliloti'''
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[[Category: Yang, H.]]
[[Category: Yang, H.]]
[[Category: Ye, J.]]
[[Category: Ye, J.]]
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[[Category: alpha/beta]]
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[[Category: Alpha/beta]]
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[[Category: flavoprotein]]
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[[Category: Flavoprotein]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 14:25:00 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 04:45:14 2008''
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Revision as of 11:25, 4 May 2008

Template:STRUCTURE 2q62

Crystal Structure of ArsH from Sinorhizobium meliloti


Overview

Purified ArsH from Sinorhizobium meliloti exhibits NADPH:FMN-dependent reduction of molecular O2 to hydrogen peroxide and catalyzes reduction of azo dyes. The structure of ArsH was determined at 1.8A resolution. ArsH crystallizes with eight molecules in the asymmetric unit forming two tetramers. Each monomer has a core domain with a central five-stranded parallel beta-sheet and two monomers interact to form a classical flavodoxin-like dimer. The N- and C-terminal extensions of ArsH are involved in interactions between subunits and tetramer formation. The structure may provide insight in how ArsH participates in arsenic detoxification.

About this Structure

2Q62 is a Single protein structure of sequence from Sinorhizobium meliloti. Full crystallographic information is available from OCA.

Reference

Crystal structure of the flavoprotein ArsH from Sinorhizobium meliloti., Ye J, Yang HC, Rosen BP, Bhattacharjee H, FEBS Lett. 2007 Aug 21;581(21):3996-4000. Epub 2007 Jul 25. PMID:17673204 Page seeded by OCA on Sun May 4 14:25:00 2008

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