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2tmk

From Proteopedia

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[[Image:2tmk.jpg|left|200px]]
[[Image:2tmk.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 2tmk |SIZE=350|CAPTION= <scene name='initialview01'>2tmk</scene>, resolution 2.4&Aring;
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The line below this paragraph, containing "STRUCTURE_2tmk", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=ATM:3&#39;-AZIDO-3&#39;-DEOXYTHYMIDINE-5&#39;-MONOPHOSPHATE'>ATM</scene>, <scene name='pdbligand=SO4:SULFATE+ION'>SO4</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/dTMP_kinase dTMP kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.4.9 2.7.4.9] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= CDC8 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=4932 Saccharomyces cerevisiae])
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-->
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|DOMAIN=
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{{STRUCTURE_2tmk| PDB=2tmk | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=2tmk FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=2tmk OCA], [http://www.ebi.ac.uk/pdbsum/2tmk PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=2tmk RCSB]</span>
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}}
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'''YEAST THYMIDYLATE KINASE COMPLEXED WITH 3'-AZIDO-3'-DEOXYTHYMIDINE MONOPHOSPHATE (AZT-MP)'''
'''YEAST THYMIDYLATE KINASE COMPLEXED WITH 3'-AZIDO-3'-DEOXYTHYMIDINE MONOPHOSPHATE (AZT-MP)'''
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[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: dTMP kinase]]
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[[Category: DTMP kinase]]
[[Category: Lavie, A.]]
[[Category: Lavie, A.]]
[[Category: Schlichting, I.]]
[[Category: Schlichting, I.]]
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[[Category: azt]]
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[[Category: Azt]]
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[[Category: enzyme]]
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[[Category: Enzyme]]
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[[Category: kinase]]
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[[Category: Kinase]]
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[[Category: thymidine activation pathway]]
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[[Category: Thymidine activation pathway]]
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[[Category: transferase (phosphotransferase)]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 17:24:42 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:03:59 2008''
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Revision as of 14:24, 4 May 2008

Image:2tmk.jpg

Template:STRUCTURE 2tmk

YEAST THYMIDYLATE KINASE COMPLEXED WITH 3'-AZIDO-3'-DEOXYTHYMIDINE MONOPHOSPHATE (AZT-MP)


About this Structure

2TMK is a Single protein structure of sequence from Saccharomyces cerevisiae. Full crystallographic information is available from OCA.

Reference

Structure of thymidylate kinase reveals the cause behind the limiting step in AZT activation., Lavie A, Vetter IR, Konrad M, Goody RS, Reinstein J, Schlichting I, Nat Struct Biol. 1997 Aug;4(8):601-4. PMID:9253404 Page seeded by OCA on Sun May 4 17:24:42 2008

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OCA

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