361d

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[[Image:361d.gif|left|200px]]
[[Image:361d.gif|left|200px]]
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{{Structure
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|PDB= 361d |SIZE=350|CAPTION= <scene name='initialview01'>361d</scene>, resolution 3.000&Aring;
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The line below this paragraph, containing "STRUCTURE_361d", creates the "Structure Box" on the page.
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|SITE=
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>, <scene name='pdbligand=U:URIDINE-5&#39;-MONOPHOSPHATE'>U</scene>
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|DOMAIN=
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{{STRUCTURE_361d| PDB=361d | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=361d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=361d OCA], [http://www.ebi.ac.uk/pdbsum/361d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=361d RCSB]</span>
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'''CRYSTAL STRUCTURE OF DOMAIN E OF THERMUS FLAVUS 5S RRNA: A HELICAL RNA-STRUCTURE INCLUDING A TETRALOOP'''
'''CRYSTAL STRUCTURE OF DOMAIN E OF THERMUS FLAVUS 5S RRNA: A HELICAL RNA-STRUCTURE INCLUDING A TETRALOOP'''
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==About this Structure==
==About this Structure==
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361D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=361D OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=361D OCA].
==Reference==
==Reference==
Crystal structure of domain E of Thermus flavus 5S rRNA: a helical RNA structure including a hairpin loop., Perbandt M, Nolte A, Lorenz S, Bald R, Betzel C, Erdmann VA, FEBS Lett. 1998 Jun 12;429(2):211-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9650592 9650592]
Crystal structure of domain E of Thermus flavus 5S rRNA: a helical RNA structure including a hairpin loop., Perbandt M, Nolte A, Lorenz S, Bald R, Betzel C, Erdmann VA, FEBS Lett. 1998 Jun 12;429(2):211-5. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9650592 9650592]
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[[Category: Protein complex]]
 
[[Category: Betzel, C.]]
[[Category: Betzel, C.]]
[[Category: Erdmann, V A.]]
[[Category: Erdmann, V A.]]
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[[Category: Nolte, A.]]
[[Category: Nolte, A.]]
[[Category: Perbandt, M.]]
[[Category: Perbandt, M.]]
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[[Category: hairpin]]
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[[Category: Hairpin]]
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[[Category: mismatched]]
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[[Category: Mismatched]]
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[[Category: rna]]
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[[Category: Rna]]
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[[Category: single strand]]
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[[Category: Single strand]]
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[[Category: tetraloop]]
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[[Category: Tetraloop]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 20:17:18 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:21:47 2008''
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Revision as of 17:17, 4 May 2008

Image:361d.gif

Template:STRUCTURE 361d

CRYSTAL STRUCTURE OF DOMAIN E OF THERMUS FLAVUS 5S RRNA: A HELICAL RNA-STRUCTURE INCLUDING A TETRALOOP


Overview

The synthetic RNA fragment 5'-CUGGGCGG(GCGA)CCGCCUGG (nucleotides in parentheses indicate the loop region) corresponds to the natural sequence of domain E from nucleotides 79-97 of the Thermus flavus 5S rRNA including a hairpin loop. The RNA structure determined at 3.0 A and refined to an R-value of 24.1% also represents the first X-ray structure GNRA tetraloop. The loop is in distinctly different conformation from other GNRA tetraloops analyzed by NMR. The conformation of the two molecules in the asymmetric unit is influenced and stabilized by specific intermolecular contacts. The structural features presented here give evidence for the ability of RNA molecules to adapt to specific environments.

About this Structure

Full crystallographic information is available from OCA.

Reference

Crystal structure of domain E of Thermus flavus 5S rRNA: a helical RNA structure including a hairpin loop., Perbandt M, Nolte A, Lorenz S, Bald R, Betzel C, Erdmann VA, FEBS Lett. 1998 Jun 12;429(2):211-5. PMID:9650592 Page seeded by OCA on Sun May 4 20:17:18 2008

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