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3b2v

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[[Image:3b2v.jpg|left|200px]]
[[Image:3b2v.jpg|left|200px]]
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{{Structure
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<!--
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|PDB= 3b2v |SIZE=350|CAPTION= <scene name='initialview01'>3b2v</scene>, resolution 3.30&Aring;
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The line below this paragraph, containing "STRUCTURE_3b2v", creates the "Structure Box" on the page.
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|SITE= <scene name='pdbsite=AC1:Nag+Binding+Site+For+Residue+A+3281'>AC1</scene>, <scene name='pdbsite=AC2:Nag+Binding+Site+For+Residue+A+3282'>AC2</scene>, <scene name='pdbsite=AC3:Ndg+Binding+Site+For+Residue+A+3371'>AC3</scene>, <scene name='pdbsite=AC4:Nag+Binding+Site+For+Residue+A+3891'>AC4</scene>, <scene name='pdbsite=AC5:Nag+Binding+Site+For+Residue+A+4201'>AC5</scene> and <scene name='pdbsite=AC6:Nag+Binding+Site+For+Residue+A+5041'>AC6</scene>
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=BMA:BETA-D-MANNOSE'>BMA</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene>, <scene name='pdbligand=NDG:2-(ACETYLAMINO)-2-DEOXY-A-D-GLUCOPYRANOSE'>NDG</scene>
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or the SCENE parameter (which sets the initial scene displayed when the page is loaded),
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|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Receptor_protein-tyrosine_kinase Receptor protein-tyrosine kinase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.7.10.1 2.7.10.1] </span>
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or leave the SCENE parameter empty for the default display.
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|GENE= EGFR ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]), EGFR, ERBB1 ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens])
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-->
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|DOMAIN=
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{{STRUCTURE_3b2v| PDB=3b2v | SCENE= }}
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|RELATEDENTRY=[[3b2u|3B2U]]
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=3b2v FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=3b2v OCA], [http://www.ebi.ac.uk/pdbsum/3b2v PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=3b2v RCSB]</span>
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}}
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'''Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8'''
'''Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8'''
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[[Category: Kussie, P.]]
[[Category: Kussie, P.]]
[[Category: Li, S.]]
[[Category: Li, S.]]
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[[Category: alternative splicing]]
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[[Category: Alternative splicing]]
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[[Category: anti-oncogene]]
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[[Category: Anti-oncogene]]
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[[Category: antigen:antibody complex]]
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[[Category: Antigen:antibody complex]]
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[[Category: antitumor]]
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[[Category: Antitumor]]
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[[Category: atp-binding]]
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[[Category: Atp-binding]]
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[[Category: cell cycle]]
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[[Category: Cell cycle]]
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[[Category: cell surface receptor]]
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[[Category: Cell surface receptor]]
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[[Category: disease mutation]]
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[[Category: Disease mutation]]
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[[Category: drug]]
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[[Category: Drug]]
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[[Category: fab fragment]]
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[[Category: Fab fragment]]
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[[Category: glycoprotein]]
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[[Category: Glycoprotein]]
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[[Category: immune system/transferase complex]]
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[[Category: Immune system/transferase complex]]
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[[Category: kinase]]
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[[Category: Kinase]]
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[[Category: membrane]]
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[[Category: Membrane]]
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[[Category: nucleotide-binding]]
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[[Category: Nucleotide-binding]]
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[[Category: phosphoprotein]]
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[[Category: Phosphoprotein]]
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[[Category: polymorphism]]
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[[Category: Polymorphism]]
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[[Category: secreted]]
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[[Category: Secreted]]
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[[Category: transferase]]
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[[Category: Transferase]]
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[[Category: transmembrane]]
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[[Category: Transmembrane]]
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[[Category: tyrosine-protein kinase]]
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[[Category: Tyrosine-protein kinase]]
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[[Category: ubl conjugation]]
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[[Category: Ubl conjugation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 20:20:16 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:22:31 2008''
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Revision as of 17:20, 4 May 2008

Image:3b2v.jpg

Template:STRUCTURE 3b2v

Crystal structure of the extracellular region of the epidermal growth factor receptor in complex with the Fab fragment of IMC-11F8


Disease

Known disease associated with this structure: Adenocarcinoma of lung, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, response to tyrosine kinase inhibitor in OMIM:[131550], Nonsmall cell lung cancer, susceptibility to OMIM:[131550]

About this Structure

3B2V is a Protein complex structure of sequences from Homo sapiens. Full crystallographic information is available from OCA. Page seeded by OCA on Sun May 4 20:20:16 2008

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OCA

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