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402d
From Proteopedia
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[[Image:402d.gif|left|200px]] | [[Image:402d.gif|left|200px]] | ||
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| - | + | {{STRUCTURE_402d| PDB=402d | SCENE= }} | |
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'''5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3'''' | '''5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3'''' | ||
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==About this Structure== | ==About this Structure== | ||
| - | + | Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=402D OCA]. | |
==Reference== | ==Reference== | ||
Structure of an RNA internal loop consisting of tandem C-A+ base pairs., Jang SB, Hung LW, Chi YI, Holbrook EL, Carter RJ, Holbrook SR, Biochemistry. 1998 Aug 25;37(34):11726-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9718295 9718295] | Structure of an RNA internal loop consisting of tandem C-A+ base pairs., Jang SB, Hung LW, Chi YI, Holbrook EL, Carter RJ, Holbrook SR, Biochemistry. 1998 Aug 25;37(34):11726-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9718295 9718295] | ||
| - | [[Category: Protein complex]] | ||
[[Category: Carter, R.]] | [[Category: Carter, R.]] | ||
[[Category: Chi, Y I.]] | [[Category: Chi, Y I.]] | ||
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[[Category: Hung, L W.]] | [[Category: Hung, L W.]] | ||
[[Category: Jang, S B.]] | [[Category: Jang, S B.]] | ||
| - | [[Category: | + | [[Category: Rna double helix]] |
| - | [[Category: | + | [[Category: Rna with tandem c-a+ base pair]] |
| - | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 22:16:06 2008'' | |
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | |
Revision as of 19:16, 4 May 2008
5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3'
Overview
The crystal structure of the RNA octamer 5'-CGC(CA)GCG-3' has been determined from X-ray diffraction data to 2.3 A resolution. In the crystal, this oligomer forms a self-complementary double helix in the asymmetric unit. Tandem non-Watson-Crick C-A and A-C base pairs comprise an internal loop in the middle of the duplex, which is incorporated with little distortion of the A-form double helix. From the geometry of the C-A base pairs, it is inferred that the adenosine imino group is protonated and donates a hydrogen bond to the carbonyl group of the cytosine. The wobble geometry of the C-A+ base pairs is very similar to that of the common U-G non-Watson-Crick pair.
About this Structure
Full crystallographic information is available from OCA.
Reference
Structure of an RNA internal loop consisting of tandem C-A+ base pairs., Jang SB, Hung LW, Chi YI, Holbrook EL, Carter RJ, Holbrook SR, Biochemistry. 1998 Aug 25;37(34):11726-31. PMID:9718295 Page seeded by OCA on Sun May 4 22:16:06 2008
