402d

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[[Image:402d.gif|left|200px]]
[[Image:402d.gif|left|200px]]
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{{Structure
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|PDB= 402d |SIZE=350|CAPTION= <scene name='initialview01'>402d</scene>, resolution 2.300&Aring;
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The line below this paragraph, containing "STRUCTURE_402d", creates the "Structure Box" on the page.
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|SITE=
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You may change the PDB parameter (which sets the PDB file loaded into the applet)
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|LIGAND= <scene name='pdbligand=A:ADENOSINE-5&#39;-MONOPHOSPHATE'>A</scene>, <scene name='pdbligand=C:CYTIDINE-5&#39;-MONOPHOSPHATE'>C</scene>, <scene name='pdbligand=G:GUANOSINE-5&#39;-MONOPHOSPHATE'>G</scene>
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{{STRUCTURE_402d| PDB=402d | SCENE= }}
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|RELATEDENTRY=
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|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=402d FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=402d OCA], [http://www.ebi.ac.uk/pdbsum/402d PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=402d RCSB]</span>
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}}
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'''5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3''''
'''5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3''''
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==About this Structure==
==About this Structure==
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402D is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/ ]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=402D OCA].
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Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=402D OCA].
==Reference==
==Reference==
Structure of an RNA internal loop consisting of tandem C-A+ base pairs., Jang SB, Hung LW, Chi YI, Holbrook EL, Carter RJ, Holbrook SR, Biochemistry. 1998 Aug 25;37(34):11726-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9718295 9718295]
Structure of an RNA internal loop consisting of tandem C-A+ base pairs., Jang SB, Hung LW, Chi YI, Holbrook EL, Carter RJ, Holbrook SR, Biochemistry. 1998 Aug 25;37(34):11726-31. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/9718295 9718295]
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[[Category: Protein complex]]
 
[[Category: Carter, R.]]
[[Category: Carter, R.]]
[[Category: Chi, Y I.]]
[[Category: Chi, Y I.]]
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[[Category: Hung, L W.]]
[[Category: Hung, L W.]]
[[Category: Jang, S B.]]
[[Category: Jang, S B.]]
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[[Category: rna double helix]]
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[[Category: Rna double helix]]
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[[Category: rna with tandem c-a+ base pair]]
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[[Category: Rna with tandem c-a+ base pair]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Sun May 4 22:16:06 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Mar 31 05:36:45 2008''
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Revision as of 19:16, 4 May 2008

Image:402d.gif

Template:STRUCTURE 402d

5'-R(*CP*GP*CP*CP*AP*GP*CP*G)-3'


Overview

The crystal structure of the RNA octamer 5'-CGC(CA)GCG-3' has been determined from X-ray diffraction data to 2.3 A resolution. In the crystal, this oligomer forms a self-complementary double helix in the asymmetric unit. Tandem non-Watson-Crick C-A and A-C base pairs comprise an internal loop in the middle of the duplex, which is incorporated with little distortion of the A-form double helix. From the geometry of the C-A base pairs, it is inferred that the adenosine imino group is protonated and donates a hydrogen bond to the carbonyl group of the cytosine. The wobble geometry of the C-A+ base pairs is very similar to that of the common U-G non-Watson-Crick pair.

About this Structure

Full crystallographic information is available from OCA.

Reference

Structure of an RNA internal loop consisting of tandem C-A+ base pairs., Jang SB, Hung LW, Chi YI, Holbrook EL, Carter RJ, Holbrook SR, Biochemistry. 1998 Aug 25;37(34):11726-31. PMID:9718295 Page seeded by OCA on Sun May 4 22:16:06 2008

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