2odj
From Proteopedia
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'''Crystal structure of the outer membrane protein OprD from Pseudomonas aeruginosa''' | '''Crystal structure of the outer membrane protein OprD from Pseudomonas aeruginosa''' | ||
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| + | ==Overview== | ||
| + | OprD proteins form a large family of substrate-specific outer-membrane channels in Gram-negative bacteria. We report here the X-ray crystal structure of OprD from Pseudomonas aeruginosa, which reveals a monomeric 18-stranded beta-barrel characterized by a very narrow pore constriction, with a positively charged basic ladder on one side and an electronegative pocket on the other side. The location of highly conserved residues in OprD suggests that the structure represents the general architecture of OprD channels. | ||
==About this Structure== | ==About this Structure== | ||
2ODJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ODJ OCA]. | 2ODJ is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Pseudomonas_aeruginosa Pseudomonas aeruginosa]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=2ODJ OCA]. | ||
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| + | ==Reference== | ||
| + | Structural insight into OprD substrate specificity., Biswas S, Mohammad MM, Patel DR, Movileanu L, van den Berg B, Nat Struct Mol Biol. 2007 Nov;14(11):1108-9. Epub 2007 Oct 21. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/17952093 17952093] | ||
[[Category: Pseudomonas aeruginosa]] | [[Category: Pseudomonas aeruginosa]] | ||
[[Category: Single protein]] | [[Category: Single protein]] | ||
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[[Category: Beta-barrel]] | [[Category: Beta-barrel]] | ||
[[Category: Outer membrane protein]] | [[Category: Outer membrane protein]] | ||
| - | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on | + | ''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Wed May 7 08:49:46 2008'' |
Revision as of 05:49, 7 May 2008
Crystal structure of the outer membrane protein OprD from Pseudomonas aeruginosa
Overview
OprD proteins form a large family of substrate-specific outer-membrane channels in Gram-negative bacteria. We report here the X-ray crystal structure of OprD from Pseudomonas aeruginosa, which reveals a monomeric 18-stranded beta-barrel characterized by a very narrow pore constriction, with a positively charged basic ladder on one side and an electronegative pocket on the other side. The location of highly conserved residues in OprD suggests that the structure represents the general architecture of OprD channels.
About this Structure
2ODJ is a Single protein structure of sequence from Pseudomonas aeruginosa. Full crystallographic information is available from OCA.
Reference
Structural insight into OprD substrate specificity., Biswas S, Mohammad MM, Patel DR, Movileanu L, van den Berg B, Nat Struct Mol Biol. 2007 Nov;14(11):1108-9. Epub 2007 Oct 21. PMID:17952093 Page seeded by OCA on Wed May 7 08:49:46 2008
