1hjz
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(New page: 200px<br /> <applet load="1hjz" size="450" color="white" frame="true" align="right" spinBox="true" caption="1hjz, resolution 1.7Å" /> '''CRYSTAL STRUCTURE OF...)
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Revision as of 17:22, 29 October 2007
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CRYSTAL STRUCTURE OF AF1521 PROTEIN CONTAINING A MACROH2A DOMAIN
Overview
MacroH2A is an unusual histone H2A variant that has an extensive, C-terminal tail that comprises approximately two thirds of the protein., The C-terminal non-histone domain of macroH2A is also found in a number of, other proteins and has been termed the macro domain. Here we report the, crystal structure to 1.7A of AF1521, a protein consisting of a stand-alone, macro domain from Archaeoglobus fulgidus. The structure has a mixed, alpha/beta fold that closely resembles the N-terminal DNA binding domain, of the Escherichia coli leucine aminopeptidase PepA. The structure also, shows some similarity to members of the P-loop family of nucleotide, hydrolases.
About this Structure
1HJZ is a [Single protein] structure of sequence from [Archaeoglobus fulgidus] with MES as [ligand]. Full crystallographic information is available from [OCA].
Reference
The crystal structure of AF1521 a protein from Archaeoglobus fulgidus with homology to the non-histone domain of macroH2A., Allen MD, Buckle AM, Cordell SC, Lowe J, Bycroft M, J Mol Biol. 2003 Jul 11;330(3):503-11. PMID:12842467
Page seeded by OCA on Mon Oct 29 19:27:36 2007
