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Template:STRUCTURE 1b41
From Proteopedia
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| - | {{ | + | {{StructureD |
| - | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE=350|CAPTION= 1b41, resolution 2.76Å (<scene name='initialview01'>initial scene</scene>) | + | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1b41, resolution 2.76Å (<scene name='initialview01'>initial scene</scene>)}}} |
| - | + | |LIGAND= <scene name='pdbligand=NDG:SUGAR+(N-ACETYL-D-GLUCOSAMINE)'>NDG</scene> | |
| - | |LIGAND= <scene name='pdbligand= | + | |
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span> | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Acetylcholinesterase Acetylcholinesterase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=3.1.1.7 3.1.1.7] </span> | ||
|GENE= ACHE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | |GENE= ACHE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=9606 Homo sapiens]) | ||
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00312 Esterase_lipase], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00135 COesterase], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00206 snake_toxin]</span> | |DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00312 Esterase_lipase], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00135 COesterase], [http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00206 snake_toxin]</span> | ||
| - | | | + | |NONSTDRES=<scene name='pdbligand=FUC:ALPHA-L-FUCOSE'>FUC</scene>, <scene name='pdbligand=NAG:N-ACETYL-D-GLUCOSAMINE'>NAG</scene> |
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b41 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b41 OCA], [http://www.ebi.ac.uk/pdbsum/1b41 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1b41 RCSB]</span> | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1b41 FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1b41 OCA], [http://www.ebi.ac.uk/pdbsum/1b41 PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1b41 RCSB]</span> | ||
| + | |FUNCTION={{GO|id=GO:0042803 | text = protein homodimerization activity}}{{GO|id=GO:0005518 | text = collagen binding}}{{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0003990 | text = acetylcholinesterase activity}}{{GO|id=GO:0017171 | text = serine hydrolase activity}}{{GO|id=GO:0042166 | text = acetylcholine binding}}{{GO|id=GO:0004104 | text = cholinesterase activity}}{{GO|id=GO:0001540 | text = beta-amyloid binding}}{{GO|id=GO:0043237 | text = laminin-1 binding}} | ||
| + | |PROCESS={{GO|id=GO:0008283 | text = cell proliferation}}{{GO|id=GO:0002076 | text = osteoblast development}}{{GO|id=GO:0009611 | text = response to wounding}}{{GO|id=GO:0006260 | text = DNA replication}}{{GO|id=GO:0007155 | text = cell adhesion}}{{GO|id=GO:0042982 | text = amyloid precursor protein metabolic process}}{{GO|id=GO:0001507 | text = acetylcholine catabolic process in synaptic cleft}}{{GO|id=GO:0050714 | text = positive regulation of protein secretion}}{{GO|id=GO:0006581 | text = acetylcholine catabolic process}}{{GO|id=GO:0007416 | text = synaptogenesis}}{{GO|id=GO:0032223 | text = negative regulation of synaptic transmission, cholinergic}}{{GO|id=GO:0042135 | text = neurotransmitter catabolic process}}{{GO|id=GO:0007399 | text = nervous system development}}{{GO|id=GO:0007517 | text = muscle development}} | ||
| + | |COMPONENT={{GO|id=GO:0005576 | text = extracellular region}}{{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0005605 | text = basal lamina}}{{GO|id=GO:0030054 | text = cell junction}}{{GO|id=GO:0045202 | text = synapse}}{{GO|id=GO:0005794 | text = Golgi apparatus}}{{GO|id=GO:0048471 | text = perinuclear region of cytoplasm}} | ||
| + | |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1b41A00 1B41A00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1b41B00 1B41B00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014788 Ipr014788], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000997 Ipr000997], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002018 Ipr002018]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00135 PF00135]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=34621 d1b41a_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=44409 d1b41b_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P22303 P22303], [http://ca.expasy.org/cgi-bin/niceprot.pl?P0C1Z0 P0C1Z0]</span> | ||
| + | |FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=P22303 P22303]</span> | ||
}} | }} | ||
