This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.
Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.
Template:STRUCTURE 1hvy
From Proteopedia
(Difference between revisions)
m (Protected "Template:STRUCTURE 1hvy" [edit=sysop:move=sysop]) |
|||
| Line 1: | Line 1: | ||
| - | {{ | + | {{StructureD |
| - | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE=350|CAPTION= 1hvy, resolution 1.90Å (<scene name='initialview01'>initial scene</scene>) | + | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1hvy, resolution 1.90Å (<scene name='initialview01'>initial scene</scene>)}}} |
| - | + | |LIGAND= <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=D16:TOMUDEX'>D16</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene> | |
| - | |LIGAND= <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME | + | |
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span> | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span> | ||
| - | |GENE= | ||
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00351 TS_Pyrimidine_HMase]</span> | |DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00351 TS_Pyrimidine_HMase]</span> | ||
| - | | | + | |NONSTDRES=<scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene> |
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hvy OCA], [http://www.ebi.ac.uk/pdbsum/1hvy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hvy RCSB]</span> | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hvy OCA], [http://www.ebi.ac.uk/pdbsum/1hvy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hvy RCSB]</span> | ||
| + | |FUNCTION={{GO|id=GO:0008168 | text = methyltransferase activity}}{{GO|id=GO:0004799 | text = thymidylate synthase activity}}{{GO|id=GO:0016740 | text = transferase activity}} | ||
| + | |PROCESS={{GO|id=GO:0009157 | text = deoxyribonucleoside monophosphate biosynthetic process}}{{GO|id=GO:0006139 | text = nucleobase, nucleoside, nucleotide and nucleic acid metabolic process}}{{GO|id=GO:0048015 | text = phosphoinositide-mediated signaling}}{{GO|id=GO:0009165 | text = nucleotide biosynthetic process}}{{GO|id=GO:0006231 | text = dTMP biosynthetic process}}{{GO|id=GO:0006260 | text = DNA replication}}{{GO|id=GO:0006281 | text = DNA repair}} | ||
| + | |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyA00 1Hvya00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyB00 1Hvyb00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyC00 1Hvyc00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyD00 1Hvyd00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014370 Ipr014370], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000398 Ipr000398]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00303 PF00303]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=41049 d1hvya_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=41050 d1hvyb_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=41051 d1hvyc_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=41052 d1hvyd_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P04818 P04818]</span> | ||
| + | |FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=P04818 P04818]</span> | ||
}} | }} | ||
