Template:STRUCTURE 1hvy
From Proteopedia
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| - | {{ | + | {{StructureD |
| - | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE=350|CAPTION= 1hvy, resolution 1.90Å (<scene name='initialview01'>initial scene</scene>) | + | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1hvy, resolution 1.90Å (<scene name='initialview01'>initial scene</scene>)}}} |
| - | + | |LIGAND= <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME</scene>, <scene name='pdbligand=D16:TOMUDEX'>D16</scene>, <scene name='pdbligand=UMP:2-DEOXYURIDINE+5-MONOPHOSPHATE'>UMP</scene> | |
| - | |LIGAND= <scene name='pdbligand=BME:BETA-MERCAPTOETHANOL'>BME | + | |
|ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span> | |ACTIVITY= <span class='plainlinks'>[http://en.wikipedia.org/wiki/Thymidylate_synthase Thymidylate synthase], with EC number [http://www.brenda-enzymes.info/php/result_flat.php4?ecno=2.1.1.45 2.1.1.45] </span> | ||
| - | |GENE= | ||
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00351 TS_Pyrimidine_HMase]</span> | |DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=cd00351 TS_Pyrimidine_HMase]</span> | ||
| - | | | + | |NONSTDRES=<scene name='pdbligand=CME:S,S-(2-HYDROXYETHYL)THIOCYSTEINE'>CME</scene> |
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hvy OCA], [http://www.ebi.ac.uk/pdbsum/1hvy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hvy RCSB]</span> | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hvy FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hvy OCA], [http://www.ebi.ac.uk/pdbsum/1hvy PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hvy RCSB]</span> | ||
| + | |FUNCTION={{GO|id=GO:0008168 | text = methyltransferase activity}}{{GO|id=GO:0004799 | text = thymidylate synthase activity}}{{GO|id=GO:0016740 | text = transferase activity}} | ||
| + | |PROCESS={{GO|id=GO:0009157 | text = deoxyribonucleoside monophosphate biosynthetic process}}{{GO|id=GO:0006139 | text = nucleobase, nucleoside, nucleotide and nucleic acid metabolic process}}{{GO|id=GO:0048015 | text = phosphoinositide-mediated signaling}}{{GO|id=GO:0009165 | text = nucleotide biosynthetic process}}{{GO|id=GO:0006231 | text = dTMP biosynthetic process}}{{GO|id=GO:0006260 | text = DNA replication}}{{GO|id=GO:0006281 | text = DNA repair}} | ||
| + | |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyA00 1Hvya00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyB00 1Hvyb00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyC00 1Hvyc00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hvyD00 1Hvyd00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR014370 Ipr014370], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000398 Ipr000398]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00303 PF00303]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=41049 d1hvya_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=41050 d1hvyb_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=41051 d1hvyc_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=41052 d1hvyd_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P04818 P04818]</span> | ||
| + | |FARESOURCES=<span class='plainlinks'>GeneCard : [http://www.genecards.org/cgi-bin/carddisp.pl?id=P04818 P04818]</span> | ||
}} | }} | ||
