1cdw

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[[Image:1cdw.gif|left|200px]]
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[[Image:1cdw.png|left|200px]]
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==Overview==
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{{ABSTRACT_8643494}}
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The TATA box-binding protein (TBP) is required by all three eukaryotic RNA polymerases for correct initiation of transcription of ribosomal, messenger, small nuclear, and transfer RNAs. The cocrystal structure of the C-terminal/core region of human TBP complexed with the TATA element of the adenovirus major late promoter has been determined at 1.9 angstroms resolution. Structural and functional analyses of the protein-DNA complex are presented, with a detailed comparison to our 1.9-angstroms resolution structure of Arabidopsis thaliana TBP2 bound to the same TATA box.
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==About this Structure==
==About this Structure==
1CDW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The following page contains interesting information on the relation of 1CDW with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb67_1.html TATA-Binding Protein]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CDW OCA].
1CDW is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Homo_sapiens Homo sapiens]. The following page contains interesting information on the relation of 1CDW with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb67_1.html TATA-Binding Protein]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1CDW OCA].
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==Reference==
 
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Crystal structure of a human TATA box-binding protein/TATA element complex., Nikolov DB, Chen H, Halay ED, Hoffman A, Roeder RG, Burley SK, Proc Natl Acad Sci U S A. 1996 May 14;93(10):4862-7. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8643494 8643494]
 
[[Category: Homo sapiens]]
[[Category: Homo sapiens]]
[[Category: Single protein]]
[[Category: Single protein]]
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[[Category: Dna binding]]
[[Category: Dna binding]]
[[Category: Transcription initiation]]
[[Category: Transcription initiation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 24 09:40:01 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 26 17:07:40 2008''

Revision as of 14:07, 26 June 2008


PDB ID 1cdw

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1cdw, resolution 1.90Å ()
Resources: FirstGlance, OCA, RCSB, PDBsum
Coordinates: save as pdb, mmCIF, xml



HUMAN TBP CORE DOMAIN COMPLEXED WITH DNA


Template:ABSTRACT 8643494

About this Structure

1CDW is a Single protein structure of sequence from Homo sapiens. The following page contains interesting information on the relation of 1CDW with [TATA-Binding Protein]. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Jun 26 17:07:40 2008

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