Template:STRUCTURE 1hsg
From Proteopedia
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| - | {{ | + | {{StructureD |
| - | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE=350|CAPTION= 1hsg, resolution 2.0Å (<scene name='initialview01'>initial scene</scene>) | + | |PDB= {{{PDB}}}|SCENE={{{SCENE}}}|SIZE={{{SIZE|350}}}|CAPTION={{{CAPTION|1hsg, resolution 2.0Å (<scene name='initialview01'>initial scene</scene>)}}} |
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|LIGAND= <scene name='pdbligand=MK1:N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY+BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE'>MK1</scene> | |LIGAND= <scene name='pdbligand=MK1:N-[2(R)-HYDROXY-1(S)-INDANYL]-5-[(2(S)-TERTIARY+BUTYLAMINOCARBONYL)-4(3-PYRIDYLMETHYL)PIPERAZINO]-4(S)-HYDROXY-2(R)-PHENYLMETHYLPENTANAMIDE'>MK1</scene> | ||
| - | |ACTIVITY= | ||
|GENE= HIV-1 PROTEASE FROM THE NY5 ISOLATE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1]) | |GENE= HIV-1 PROTEASE FROM THE NY5 ISOLATE ([http://www.ncbi.nlm.nih.gov/Taxonomy/Browser/wwwtax.cgi?mode=Info&srchmode=5&id=11676 Human immunodeficiency virus 1]) | ||
|DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00077 RVP]</span> | |DOMAIN=<span class='plainlinks'>[http://www.ncbi.nlm.nih.gov/Structure/cdd/cddsrv.cgi?uid=pfam00077 RVP]</span> | ||
| - | |RELATEDENTRY= | ||
|RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hsg OCA], [http://www.ebi.ac.uk/pdbsum/1hsg PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hsg RCSB]</span> | |RESOURCES=<span class='plainlinks'>[http://oca.weizmann.ac.il/oca-docs/fgij/fg.htm?mol=1hsg FirstGlance], [http://oca.weizmann.ac.il/oca-bin/ocaids?id=1hsg OCA], [http://www.ebi.ac.uk/pdbsum/1hsg PDBsum], [http://www.rcsb.org/pdb/explore.do?structureId=1hsg RCSB]</span> | ||
| + | |FUNCTION={{GO|id=GO:0016787 | text = hydrolase activity}}{{GO|id=GO:0016779 | text = nucleotidyltransferase activity}}{{GO|id=GO:0004523 | text = ribonuclease H activity}}{{GO|id=GO:0003676 | text = nucleic acid binding}}{{GO|id=GO:0004190 | text = aspartic-type endopeptidase activity}}{{GO|id=GO:0008233 | text = peptidase activity}}{{GO|id=GO:0004519 | text = endonuclease activity}}{{GO|id=GO:0003677 | text = DNA binding}}{{GO|id=GO:0016740 | text = transferase activity}}{{GO|id=GO:0003964 | text = RNA-directed DNA polymerase activity}}{{GO|id=GO:0046872 | text = metal ion binding}}{{GO|id=GO:0005198 | text = structural molecule activity}}{{GO|id=GO:0003723 | text = RNA binding}}{{GO|id=GO:0000287 | text = magnesium ion binding}}{{GO|id=GO:0003887 | text = DNA-directed DNA polymerase activity}}{{GO|id=GO:0008270 | text = zinc ion binding}}{{GO|id=GO:0004518 | text = nuclease activity}}{{GO|id=GO:0003824 | text = catalytic activity}}{{GO|id=GO:0008907 | text = integrase activity}} | ||
| + | |PROCESS={{GO|id=GO:0016032 | text = viral reproduction}}{{GO|id=GO:0046797 | text = viral procapsid maturation}}{{GO|id=GO:0015074 | text = DNA integration}}{{GO|id=GO:0006508 | text = proteolysis}}{{GO|id=GO:0006310 | text = DNA recombination}}{{GO|id=GO:0006278 | text = RNA-dependent DNA replication}}{{GO|id=GO:0006313 | text = transposition, DNA-mediated}} | ||
| + | |COMPONENT={{GO|id=GO:0005737 | text = cytoplasm}}{{GO|id=GO:0019013 | text = viral nucleocapsid}}{{GO|id=GO:0005634 | text = nucleus}}{{GO|id=GO:0016020 | text = membrane}}{{GO|id=GO:0019028 | text = viral capsid}}{{GO|id=GO:0019012 | text = virion}} | ||
| + | |SARESOURCES=<span class='plainlinks'>CATH : [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hsgA00 1Hsga00], [http://www.cathdb.info/cgi-bin/cath/Domain.pl?domain_id=1hsgB00 1Hsgb00]<br>InterPro : [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010659 Ipr010659], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010999 Ipr010999], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001995 Ipr001995], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008916 Ipr008916], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR010661 Ipr010661], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR002156 Ipr002156], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001878 Ipr001878], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000071 Ipr000071], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000721 Ipr000721], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR012337 Ipr012337], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001037 Ipr001037], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR009007 Ipr009007], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001969 Ipr001969], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR008919 Ipr008919], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR003308 Ipr003308], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR000477 Ipr000477], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR013084 Ipr013084], [http://www.ebi.ac.uk/interpro/ISearch?query=IPR001584 Ipr001584]<br>Pfam : [http://pfam.sanger.ac.uk/family?acc=PF00077 PF00077]<br>SCOP : [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=26541 d1hsga_], [http://scop.mrc-lmb.cam.ac.uk/scop/search.cgi?search_type=SCOP&key=26542 d1hsgb_]<br>UniProt : [http://ca.expasy.org/cgi-bin/niceprot.pl?P03367 P03367]</span> | ||
}} | }} | ||
