1htm

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==Overview==
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{{ABSTRACT_8072525}}
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Low pH induces a conformational change in the influenza virus haemagglutinin, which then mediates fusion of the viral and host cell membranes. The three-dimensional structure of a fragment of the haemagglutinin in this conformation reveals a major refolding of the secondary and tertiary structure of the molecule. The apolar fusion peptide moves at least 100 A to one tip of the molecule. At the other end a helical segment unfolds, a subdomain relocates reversing the chain direction, and part of the structure becomes disordered.
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==About this Structure==
==About this Structure==
1HTM is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bacteria Bacteria]. The following page contains interesting information on the relation of 1HTM with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb76_1.html Hemagglutinin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTM OCA].
1HTM is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Bacteria Bacteria]. The following page contains interesting information on the relation of 1HTM with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb76_1.html Hemagglutinin]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1HTM OCA].
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==Reference==
 
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Structure of influenza haemagglutinin at the pH of membrane fusion., Bullough PA, Hughson FM, Skehel JJ, Wiley DC, Nature. 1994 Sep 1;371(6492):37-43. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8072525 8072525]
 
[[Category: Bacteria]]
[[Category: Bacteria]]
[[Category: Hemagglutinin]]
[[Category: Hemagglutinin]]
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[[Category: Wiley, D C.]]
[[Category: Wiley, D C.]]
[[Category: Influenza virus hemagglutinin]]
[[Category: Influenza virus hemagglutinin]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 19:12:58 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 26 17:30:29 2008''

Revision as of 14:30, 26 June 2008

Image:1htm.png

Template:STRUCTURE 1htm

STRUCTURE OF INFLUENZA HAEMAGGLUTININ AT THE PH OF MEMBRANE FUSION


Template:ABSTRACT 8072525

About this Structure

1HTM is a Protein complex structure of sequences from Bacteria. The following page contains interesting information on the relation of 1HTM with [Hemagglutinin]. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Jun 26 17:30:29 2008

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