1ytf

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==Overview==
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{{ABSTRACT_8610010}}
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The X-ray crystal structure of the transcription factor IIA (TFIIA) in complex with the TATA-box-binding protein (TBP) and TATA-element DNA is presented at 2.5 A resolution. TFIIA is composed of a beta-barrel and a four-helix bundle motif that together have a boot-like appearance. The beta-barrel extends the TBP beta-sheet and bridges over the DNA major groove immediately upstream of the TATA box. The four-helix bundle contributes substantially to the surface of the complex available for interaction with additional transcription factors.
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==About this Structure==
==About this Structure==
1YTF is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. The following page contains interesting information on the relation of 1YTF with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb67_1.html TATA-Binding Protein]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YTF OCA].
1YTF is a [[Protein complex]] structure of sequences from [http://en.wikipedia.org/wiki/Saccharomyces_cerevisiae Saccharomyces cerevisiae]. The following page contains interesting information on the relation of 1YTF with [[http://pdb.rcsb.org/pdb/static.do?p=education_discussion/molecule_of_the_month/pdb67_1.html TATA-Binding Protein]]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1YTF OCA].
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==Reference==
 
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Crystal structure of a yeast TFIIA/TBP/DNA complex., Tan S, Hunziker Y, Sargent DF, Richmond TJ, Nature. 1996 May 9;381(6578):127-51. PMID:[http://www.ncbi.nlm.nih.gov/pubmed/8610010 8610010]
 
[[Category: Protein complex]]
[[Category: Protein complex]]
[[Category: Saccharomyces cerevisiae]]
[[Category: Saccharomyces cerevisiae]]
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[[Category: Dna]]
[[Category: Dna]]
[[Category: Transcription regulation]]
[[Category: Transcription regulation]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Apr 24 09:40:28 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Thu Jun 26 18:09:14 2008''

Revision as of 15:09, 26 June 2008

Template:STRUCTURE 1ytf

YEAST TFIIA/TBP/DNA COMPLEX


Template:ABSTRACT 8610010

About this Structure

1YTF is a Protein complex structure of sequences from Saccharomyces cerevisiae. The following page contains interesting information on the relation of 1YTF with [TATA-Binding Protein]. Full crystallographic information is available from OCA.

Page seeded by OCA on Thu Jun 26 18:09:14 2008

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