This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1gsp

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1gsp.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1gsp.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1gsp| PDB=1gsp | SCENE= }}
{{STRUCTURE_1gsp| PDB=1gsp | SCENE= }}
-
'''RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS, 1 DAY'''
+
===RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS, 1 DAY===
-
==Overview==
+
{{ABSTRACT_PUBMED_9546218}}
-
Here we present a time-resolved crystallographic analysis of the hydrolysis of exo (Sp) guanosine 2',3'-cyclophosphorothioate by RNase T1. The use of a slow substrate and fast crystallization methods made it possible to perform the study with conventional data-collection techniques. The results support the idea that the hydrolysis reaction proceeds through a mechanism that is the inverse of the transesterification reaction. In addition, the structures provide an explanation for the differential behavior of RNase T1 towards exo- and endo-cyclic thiophosphates.
+
==About this Structure==
==About this Structure==
Line 26: Line 26:
[[Category: Endoribonuclease]]
[[Category: Endoribonuclease]]
[[Category: Hydrolase]]
[[Category: Hydrolase]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 17:57:43 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri Jun 27 20:32:19 2008''

Revision as of 17:32, 27 June 2008

Image:1gsp.png

Template:STRUCTURE 1gsp

RIBONUCLEASE T1 COMPLEXED WITH 2',3'-CGPS, 1 DAY

Template:ABSTRACT PUBMED 9546218

About this Structure

1GSP is a Single protein structure of sequence from Aspergillus oryzae. Full crystallographic information is available from OCA.

Reference

Hydrolysis of a slow cyclic thiophosphate substrate of RNase T1 analyzed by time-resolved crystallography., Zegers I, Loris R, Dehollander G, Fattah Haikal A, Poortmans F, Steyaert J, Wyns L, Nat Struct Biol. 1998 Apr;5(4):280-3. PMID:9546218

Page seeded by OCA on Fri Jun 27 20:32:19 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1gsp"
Personal tools