This old version of Proteopedia is provided for student assignments while the new version is undergoing repairs. Content and edits done in this old version of Proteopedia after March 1, 2026 will eventually be lost when it is retired in about June of 2026.

Apply for new accounts at the new Proteopedia. Your logins will work in both the old and new versions.


1a65

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1a65.jpg|left|200px]]
+
{{Seed}}
 +
[[Image:1a65.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1a65| PDB=1a65 | SCENE= }}
{{STRUCTURE_1a65| PDB=1a65 | SCENE= }}
-
'''TYPE-2 CU-DEPLETED LACCASE FROM COPRINUS CINEREUS'''
+
===TYPE-2 CU-DEPLETED LACCASE FROM COPRINUS CINEREUS===
-
==Overview==
+
<!--
-
Laccase catalyses the oxidation of a variety of organic substrates coupled to the reduction of oxygen to water. It is widely believed to be the simplest representative of the ubiquitous blue multi-copper oxidase family. Laccase is implicated in a wide spectrum of biological activities and, in particular, plays a key role in morphogenesis, development and lignin metabolism in fungi and plants. The structure of laccase from the fungus Coprinus cinereus has been determined by X-ray crystallography at a resolution of 2.2 A. Laccase is a monomer composed of three cupredoxin-like beta-sandwich domains, similar to that found in ascorbate oxidase. In contrast to ascorbate oxidase, however, the mononuclear type-1 Cu site lacks the axial methionine ligand and so exhibits trigonal planar coordination, consistent with its elevated redox potential. Crucially, the structure is trapped in a Cu depleted form in which the putative type-2 Cu atom is completely absent, but in which the remaining type-1 and type-3 Cu sites display full occupancy. Type-2 Cu depletion has unexpected consequences for the coordination of the remaining type-3 Cu atoms.
+
The line below this paragraph, {{ABSTRACT_PUBMED_9546223}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 9546223 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_9546223}}
==About this Structure==
==About this Structure==
Line 31: Line 35:
[[Category: Signal]]
[[Category: Signal]]
[[Category: Type-2 copper depleted]]
[[Category: Type-2 copper depleted]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 09:52:11 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:13:18 2008''

Revision as of 13:13, 30 June 2008

Image:1a65.png

Template:STRUCTURE 1a65

TYPE-2 CU-DEPLETED LACCASE FROM COPRINUS CINEREUS

Template:ABSTRACT PUBMED 9546223

About this Structure

1A65 is a Single protein structure of sequence from Coprinopsis cinerea. Full crystallographic information is available from OCA.

Reference

Crystal structure of the type-2 Cu depleted laccase from Coprinus cinereus at 2.2 A resolution., Ducros V, Brzozowski AM, Wilson KS, Brown SH, Ostergaard P, Schneider P, Yaver DS, Pedersen AH, Davies GJ, Nat Struct Biol. 1998 Apr;5(4):310-6. PMID:9546223

Page seeded by OCA on Mon Jun 30 16:13:18 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1a65"
Personal tools