1dpx
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(New page: 200px<br /><applet load="1dpx" size="450" color="white" frame="true" align="right" spinBox="true" caption="1dpx, resolution 1.65Å" /> '''STRUCTURE OF HEN EGG...)
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Revision as of 11:21, 20 November 2007
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STRUCTURE OF HEN EGG-WHITE LYSOZYME
Overview
Hen egg-white lysozyme has been crystallized at slightly alkaline pH using, 2-methyl-2,4-pentanediol (MPD) as the precipitant. The crystals are nearly, isomorphous to crystals grown at acidic pH using sodium chloride as the, precipitant. However, the growth kinetics differ markedly between the two, conditions. The major reason for this is a molecule of MPD that binds, tightly in between two lysozyme molecules and favors the growth of the, crystals along the crystallographic c direction over growth perpendicular, to it.
About this Structure
1DPX is a Single protein structure of sequence from Gallus gallus with CL as ligand. Active as Lysozyme, with EC number 3.2.1.17 Full crystallographic information is available from OCA.
Reference
Crystallization, structure solution and refinement of hen egg-white lysozyme at pH 8.0 in the presence of MPD., Weiss MS, Palm GJ, Hilgenfeld R, Acta Crystallogr D Biol Crystallogr. 2000 Aug;56(Pt 8):952-8. PMID:10944331
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