1a6s

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{{STRUCTURE_1a6s| PDB=1a6s | SCENE= }}
{{STRUCTURE_1a6s| PDB=1a6s | SCENE= }}
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'''M-DOMAIN FROM GAG POLYPROTEIN OF ROUS SARCOMA VIRUS, NMR, 20 STRUCTURES'''
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===M-DOMAIN FROM GAG POLYPROTEIN OF ROUS SARCOMA VIRUS, NMR, 20 STRUCTURES===
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==Overview==
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A biologically active construct of the retroviral M domain from the avian Rous sarcoma virus is defined and its solution structure described. This M domain is fully active in budding and infectivity without myristylation. In spite of a sequence homology level that suggests no relationship among M domains and the family of matrix proteins in mammalian retroviruses, the conserved structural elements of a central core allow an M domain sequence motif to be described for all retroviruses. The surface of the M domain has a highly clustered positive patch comprised of sequentially distant residues. An analysis of the backbone dynamics, incorporating rotational anisotropy, is used to estimate the thermodynamics of proposed domain oligomerization.
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(as it appears on PubMed at http://www.pubmed.gov), where 9642071 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9642071}}
==About this Structure==
==About this Structure==
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1A6S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6S OCA].
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1A6S is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Rous_sarcoma_virus Rous sarcoma virus]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1A6S OCA].
==Reference==
==Reference==
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[[Category: Membrane binding]]
[[Category: Membrane binding]]
[[Category: Virus structure]]
[[Category: Virus structure]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 09:54:03 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 16:15:58 2008''

Revision as of 13:16, 30 June 2008

Image:1a6s.png

Template:STRUCTURE 1a6s

M-DOMAIN FROM GAG POLYPROTEIN OF ROUS SARCOMA VIRUS, NMR, 20 STRUCTURES

Template:ABSTRACT PUBMED 9642071

About this Structure

1A6S is a Single protein structure of sequence from Rous sarcoma virus. Full experimental information is available from OCA.

Reference

Solution structure and dynamics of the bioactive retroviral M domain from Rous sarcoma virus., McDonnell JM, Fushman D, Cahill SM, Zhou W, Wolven A, Wilson CB, Nelle TD, Resh MD, Wills J, Cowburn D, J Mol Biol. 1998 Jun 19;279(4):921-8. PMID:9642071

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