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1ao7

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[[Image:1ao7.gif|left|200px]]
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{{STRUCTURE_1ao7| PDB=1ao7 | SCENE= }}
{{STRUCTURE_1ao7| PDB=1ao7 | SCENE= }}
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'''COMPLEX BETWEEN HUMAN T-CELL RECEPTOR, VIRAL PEPTIDE (TAX), AND HLA-A 0201'''
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===COMPLEX BETWEEN HUMAN T-CELL RECEPTOR, VIRAL PEPTIDE (TAX), AND HLA-A 0201===
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==Overview==
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Recognition by a T-cell antigen receptor (TCR) of peptide complexed with a major histocompatibility complex (MHC) molecule occurs through variable loops in the TCR structure which bury almost all the available peptide and a much larger area of the MHC molecule. The TCR fits diagonally across the MHC peptide-binding site in a surface feature common to all class I and class II MHC molecules, providing evidence that the nature of binding is general. A broadly applicable binding mode has implications for the mechanism of repertoire selection and the magnitude of alloreactions.
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(as it appears on PubMed at http://www.pubmed.gov), where 8906788 is the PubMed ID number.
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{{ABSTRACT_PUBMED_8906788}}
==About this Structure==
==About this Structure==
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[[Category: T-cell receptor]]
[[Category: T-cell receptor]]
[[Category: Viral peptide]]
[[Category: Viral peptide]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 10:30:10 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:16:26 2008''

Revision as of 14:16, 30 June 2008

Image:1ao7.png

Template:STRUCTURE 1ao7

COMPLEX BETWEEN HUMAN T-CELL RECEPTOR, VIRAL PEPTIDE (TAX), AND HLA-A 0201

Template:ABSTRACT PUBMED 8906788

About this Structure

1AO7 is a Protein complex structure of sequences from Homo sapiens and Human t-lymphotropic virus 1. Full crystallographic information is available from OCA.

Reference

Structure of the complex between human T-cell receptor, viral peptide and HLA-A2., Garboczi DN, Ghosh P, Utz U, Fan QR, Biddison WE, Wiley DC, Nature. 1996 Nov 14;384(6605):134-41. PMID:8906788

Page seeded by OCA on Mon Jun 30 17:16:26 2008

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