1apc

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[[Image:1apc.gif|left|200px]]
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{{STRUCTURE_1apc| PDB=1apc | SCENE= }}
{{STRUCTURE_1apc| PDB=1apc | SCENE= }}
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'''SOLUTION STRUCTURE OF APOCYTOCHROME B562'''
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===SOLUTION STRUCTURE OF APOCYTOCHROME B562===
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==Overview==
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The apoprotein is an important intermediate on the folding pathways of many haem proteins, yet a detailed structure of such an intermediate has remained elusive. Here we present the structure of apocytochrome b562 obtained by NMR spectroscopy. The apoprotein has a topology similar to the holoprotein. Nevertheless, significant differences in helix-helix packing between the two are evident. Much of the haem binding pocket in the apoprotein is preserved but exposed to solvent creating a large cavern. As apocytochrome b562 displays many of the physical characteristics ascribed to the molten globule state, these results help ellucidate the origin of several properties of the protein molten globule.
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{{ABSTRACT_PUBMED_7656004}}
==About this Structure==
==About this Structure==
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1APC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full crystallographic information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1APC OCA].
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1APC is a [[Single protein]] structure of sequence from [http://en.wikipedia.org/wiki/Escherichia_coli Escherichia coli]. Full experimental information is available from [http://oca.weizmann.ac.il/oca-bin/ocashort?id=1APC OCA].
==Reference==
==Reference==
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[[Category: Wand, A J.]]
[[Category: Wand, A J.]]
[[Category: Electron transport]]
[[Category: Electron transport]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:21:03 2008''

Revision as of 14:21, 30 June 2008

Image:1apc.png

Template:STRUCTURE 1apc

SOLUTION STRUCTURE OF APOCYTOCHROME B562

Template:ABSTRACT PUBMED 7656004

About this Structure

1APC is a Single protein structure of sequence from Escherichia coli. Full experimental information is available from OCA.

Reference

Solution structure of apocytochrome b562., Feng Y, Sligar SG, Wand AJ, Nat Struct Biol. 1994 Jan;1(1):30-5. PMID:7656004

Page seeded by OCA on Mon Jun 30 17:21:03 2008

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