1b0b

From Proteopedia

(Difference between revisions)
Jump to: navigation, search
Line 1: Line 1:
-
[[Image:1b0b.gif|left|200px]]
+
{{Seed}}
 +
[[Image:1b0b.png|left|200px]]
<!--
<!--
Line 9: Line 10:
{{STRUCTURE_1b0b| PDB=1b0b | SCENE= }}
{{STRUCTURE_1b0b| PDB=1b0b | SCENE= }}
-
'''HEMOGLOBIN I FROM THE CLAM LUCINA PECTINATA, CYANIDE COMPLEX AT 100 KELVIN'''
+
===HEMOGLOBIN I FROM THE CLAM LUCINA PECTINATA, CYANIDE COMPLEX AT 100 KELVIN===
-
==Overview==
+
<!--
-
The x-ray crystal structures of the cyanide derivative of Lucina pectinata monomeric hemoglobin I (L. pectinata HbI) and sperm whale (Physeter catodon) myoglobin (Mb), generally taken as reference models for monomeric hemoproteins carrying hydrogen sulfide and oxygen, respectively, have been determined at 1.9 A (R-factor = 0. 184), and 1.8 A (R-factor = 0.181) resolution, respectively, at room temperature (lambda = 1.542 A). Moreover, the x-ray crystal structure of the L. pectinata HbI:cyanide derivative has been studied at 1.4-A resolution (R-factor = 0.118) and 100 K (on a synchrotron source lambda = 0.998 A). At room temperature, the cyanide ligand is roughly parallel to the heme plane of L. pectinata HbI, being located approximately 2.5 A from the iron atom. On the other hand, the crystal structure of the L. pectinata HbI:cyanide derivative at 100 K shows that the diatomic ligand is coordinated to the iron atom in an orientation almost perpendicular to the heme (the Fe-C distance being 1.95 A), adopting a coordination geometry strictly reminescent of that observed in sperm whale Mb, at room temperature. The unusual cyanide distal site orientation observed in L. pectinata HbI, at room temperature, may reflect reduction of the heme Fe(III) atom induced by free radical species during x-ray data collection using Cu Kalpha radiation.
+
The line below this paragraph, {{ABSTRACT_PUBMED_10423453}}, adds the Publication Abstract to the page
 +
(as it appears on PubMed at http://www.pubmed.gov), where 10423453 is the PubMed ID number.
 +
-->
 +
{{ABSTRACT_PUBMED_10423453}}
==About this Structure==
==About this Structure==
Line 30: Line 34:
[[Category: Oxygen transport]]
[[Category: Oxygen transport]]
[[Category: Sulfide carrier]]
[[Category: Sulfide carrier]]
-
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 10:54:40 2008''
+
 
 +
''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 17:58:12 2008''

Revision as of 14:58, 30 June 2008

Image:1b0b.png

Template:STRUCTURE 1b0b

HEMOGLOBIN I FROM THE CLAM LUCINA PECTINATA, CYANIDE COMPLEX AT 100 KELVIN

Template:ABSTRACT PUBMED 10423453

About this Structure

1B0B is a Single protein structure of sequence from Lucina pectinata. Full crystallographic information is available from OCA.

Reference

Cyanide binding to Lucina pectinata hemoglobin I and to sperm whale myoglobin: an x-ray crystallographic study., Bolognesi M, Rosano C, Losso R, Borassi A, Rizzi M, Wittenberg JB, Boffi A, Ascenzi P, Biophys J. 1999 Aug;77(2):1093-9. PMID:10423453

Page seeded by OCA on Mon Jun 30 17:58:12 2008

Proteopedia Page Contributors and Editors (what is this?)

OCA

Retrieved from "http://52.214.119.220/wiki/index.php/1b0b"
Personal tools