1bdj

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[[Image:1bdj.gif|left|200px]]
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{{STRUCTURE_1bdj| PDB=1bdj | SCENE= }}
{{STRUCTURE_1bdj| PDB=1bdj | SCENE= }}
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'''COMPLEX STRUCTURE OF HPT DOMAIN AND CHEY'''
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===COMPLEX STRUCTURE OF HPT DOMAIN AND CHEY===
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==Overview==
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The three-dimensional structure of the HPt domain of ArcB complexed with CheY has been determined using the molecular-replacement method. The structure was refined to a crystallographic R factor of 18.3% at 2.68 A resolution. The final model included 1899 protein atoms (117 residues from the HPt domain and 128 residues from CheY), one sulfate ion and 44 solvent molecules. In the crystal, CheY molecules stacked along the a axis of the cell with no interactions between neighbouring rows and the HPt domain bridged the CheY molecules. The phosphodonor residue His715 was fully exposed to the solvent region, even though the HPt domain was in contact with four molecules of CheY. CheY showed significant conformational change. This indicates that the HPt domain has a rigid structure when complexed with CheY.
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(as it appears on PubMed at http://www.pubmed.gov), where 10393292 is the PubMed ID number.
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{{ABSTRACT_PUBMED_10393292}}
==About this Structure==
==About this Structure==
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[[Category: Response regulator]]
[[Category: Response regulator]]
[[Category: Two-component system]]
[[Category: Two-component system]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 11:22:32 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 18:54:09 2008''

Revision as of 15:54, 30 June 2008

Image:1bdj.png

Template:STRUCTURE 1bdj

COMPLEX STRUCTURE OF HPT DOMAIN AND CHEY

Template:ABSTRACT PUBMED 10393292

About this Structure

1BDJ is a Protein complex structure of sequences from Escherichia coli. Full crystallographic information is available from OCA.

Reference

Structure of the histidine-containing phosphotransfer (HPt) domain of the anaerobic sensor protein ArcB complexed with the chemotaxis response regulator CheY., Kato M, Shimizu T, Mizuno T, Hakoshima T, Acta Crystallogr D Biol Crystallogr. 1999 Jul;55(Pt 7):1257-63. PMID:10393292

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