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1bg1

From Proteopedia

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[[Image:1bg1.gif|left|200px]]
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{{STRUCTURE_1bg1| PDB=1bg1 | SCENE= }}
{{STRUCTURE_1bg1| PDB=1bg1 | SCENE= }}
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'''TRANSCRIPTION FACTOR STAT3B/DNA COMPLEX'''
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===TRANSCRIPTION FACTOR STAT3B/DNA COMPLEX===
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==Overview==
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STAT proteins are a family of eukaryotic transcription factors that mediate the response to a large number of cytokines and growth factors. Upon activation by cell-surface receptors or their associated kinases, STAT proteins dimerize, translocate to the nucleus and bind to specific promoter sequences on their target genes. Here we report the first crystal structure of a STAT protein bound to its DNA recognition site at 2.25 A resolution. The structure provides insight into the various steps by which STAT proteins deliver a response signal directly from the cell membrane to their target genes in the nucleus.
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The line below this paragraph, {{ABSTRACT_PUBMED_9671298}}, adds the Publication Abstract to the page
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(as it appears on PubMed at http://www.pubmed.gov), where 9671298 is the PubMed ID number.
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{{ABSTRACT_PUBMED_9671298}}
==About this Structure==
==About this Structure==
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[[Category: Protein-dna complex]]
[[Category: Protein-dna complex]]
[[Category: Transcription factor]]
[[Category: Transcription factor]]
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Fri May 2 11:27:52 2008''
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''Page seeded by [http://oca.weizmann.ac.il/oca OCA ] on Mon Jun 30 19:04:57 2008''

Revision as of 16:05, 30 June 2008

Image:1bg1.png

Template:STRUCTURE 1bg1

TRANSCRIPTION FACTOR STAT3B/DNA COMPLEX

Template:ABSTRACT PUBMED 9671298

About this Structure

1BG1 is a Single protein structure of sequence from Mus musculus. Full crystallographic information is available from OCA.

Reference

Three-dimensional structure of the Stat3beta homodimer bound to DNA., Becker S, Groner B, Muller CW, Nature. 1998 Jul 9;394(6689):145-51. PMID:9671298

Page seeded by OCA on Mon Jun 30 19:04:57 2008

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